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Stockholders' Equity (Tables)
 12 Months Ended
Dec. 31, 2012
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Stock option activity
Options granted under the Plans vest as determined by the Company's Compensation and Stock Option Committee and expire over varying terms, but not more than ten years from the date of grant. Stock option activity for 2012, 2011, and 2010 is as follows:
 
Number of
Options
Exercise Price
per Share
Weighted Average
Exercise Price
Weighted
Average
 Remaining
Life
(Years)
Outstanding at December 31, 2009
3,345,000
$
1.23–6.18
$
3.72
6.58
Granted
700,650
5.28-15.54
9.81
Expired
(120,000
)
2.78-3.59
3.25
Forfeited
(25,000
)
4.12-6.18
4.81
Exercised
(140,000
)
1.43-6.18
3.52
Outstanding at December 31, 2010
3,760,650
$
1.23-15.54
$
4.88
6.65
Granted
671,326
2.00-9.18
5.72
Expired
(120,000
)
3.28
3.28
Forfeited
(136,900
)
1.40-9.93
4.65
Exercised
(45,327
)
2.44-3.28
3.18
Outstanding at December 31, 2011
4,129,749
$
1.23-15.54
$
5.09
6.38
Granted
1,207,452
1.43-4.60
3.80
Expired
(420,000
)
1.88-5.85
4.81
Forfeited
(128,314
)
2.26-9.18
5.05
Exercised
-
Outstanding at December 31, 2012
4,788,887
$
1.23-15.54
$
4.79
6.88
Exercisable at December 31, 2012
3,105,535
$
1.23-15.54
$
$4.85
5.80
Assumptions used to determine the fair value of stock options
The estimated fair value of each option award granted was determined on the date of grant using an option pricing model with the following assumptions for option grants during the years ended December 31, 2012, 2011 and 2010:
 
Year Ended December 31,
2012
2011
2010
Weighted average risk-free interest rate
1.11
%
2.07
%
2.54
%
Weighted average expected volatility
79.89
%
74.64
%
73.80
%
Expected volatility
77.37-84.81
%
73.88% - 79.11
%
72.16% - 75.40
%
Dividend yield
0.00
%
0.00
%
0.00
%
Weighted average expected option term (in years)
6.17
6.00
5.87
Weighted average grant date fair value
$
2.59
$
3.79
$
6.30
Non-vested options
A summary of the Company's non-vested options to purchase shares as of December 31, 2012 and changes during the twelve months ended December 31, 2012 and December 31, 2011 are presented below:

Non-Vested Options
Number of
Options
Weighted
Average
Exercise Price
 
 
Non-vested at December 31, 2010
1,362,316
$
6.39
Granted
670,826
5.72
Vested
(812,874
)
5.60
Forfeited
(61,900
)
8.58
Non-vested at December 31, 2011
1,158,368
$
6.44
Granted
1,207,452
3.80
Vested
(570,518
)
6.38
Forfeited
(111,950
)
4.79
Non-vested at December 31, 2012
1,683,352
$
4.68
 
Restricted stock activity
A summary of the Company's restricted stock activity as of December 31, 2012 and changes during the twelve months ended December 31, 2012 and December 31, 2011 are presented below:

Restricted Stock Activity
Number of Shares
Weighted Average
Grant Date Fair Value
 
 
Non-vested at December 31, 2010
67,590
$
6.71
Granted
188,277
5.67
Vested
(47,270
)
5.62
Forfeited
(15,065
)
8.35
Non-vested at December 31, 2011
193,532
$
5.84
Granted
429,720
2.83
Vested
(100,751
)
6.18
Forfeited
(21,033
)
4.39
Non-vested at December 31, 2012
501,468
$
3.26
Warrant activity
A summary of warrant activity is as follows:
 
Warrants
Exercise Price
per Share
Weighted
Average
Exercise Price
Weighted
Average
Remaining Life
(Years)
Outstanding at December 31, 2009
3,746,184
$
3.44–3.91
$
3.52
3.08
Issued
–
Exercised
(1,159,000
)
3.44–3.91
3.52
Expired
(74,250
)
3.91
3.91
Outstanding at December 31, 2010
2,512,934
$
3.44-3.60
$
3.51
2.45
Issued
–
Exercised
–
Expired
–
Outstanding at December 31, 2011
2,512,934
$
3.44-3.60
$
3.51
1.45
Issued
6,523,120
1.49-3.03 
1.65
Exercised
(2,975,457
)
1.49-1.65 
1.49
Expired
(418,017
) 
1.49 
1.49
Outstanding at December 31, 2012
5,642,580
$
1.20
$
1.20
2.24
Stock Options [Member]
  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Compensation expense recognized granted to employees
Compensation expense recognized relating to stock options granted to employees (in millions):
 
 
 
 
 
 
 
2012
 
2011
 
2010
 
Selling, general and administrative
 
$
1.7
 
 
$
2.2
 
 
$
2.5
 
Research and development
 
 
1.1
 
 
 
1.4
 
 
 
1.1
 
Total
 
$
2.8
 
 
$
3.6
 
 
$
3.6
 
 
 
 
 
 
 
 
 
 
 
 
 
Restricted Stock [Member]
  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Compensation expense recognized granted to employees
Compensation expense recognized relating to restricted stock granted to employees (in millions):
 
 
 
 
 
 
 
2012
 
2011
 
2010
 
Selling, general and administrative
 
$
0.7
 
 
$
0.5
 
 
$
0.8
 
Research and development
 
 
0.3
 
 
 
0.1
 
 
 
0.8
 
Total
 
$
1.0
 
 
$
0.6
 
 
$
1.6
 
 
 
 
 
 
 
 
 
 
 
 
 
Warrant [Member]
  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Assumptions used to determine the fair value of stock options
For the year ended December 31, 2012, the Company recorded pre-tax derivative instrument income of $2.2 million. The resulting derivative instrument liabilities totaled $3.4 million at December 31, 2012. Management expects that the warrants will either be exercised or expire worthless. The fair value of the Warrants at December 31, 2012 was determined by using an option pricing model assuming the following:
 
2012 Warrants
2009 Warrants
Expected volatility
86.08
%
87.14
%
Risk-free interest rates
0.30
%
0.20
%
Expected life (in years)
2.4
1.4