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Consolidated Statements of Comprehensive Loss (USD $)
In Thousands, except Share data, unless otherwise specified
 12 Months Ended
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Consolidated Statements of Comprehensive Loss [Abstract]      
Revenue $ 346 $ 0 $ 0
Costs of goods sold (39) 0 0
Gross profit 307 0 0
Operating expenses      
Selling, general and administrative 27,963 21,283 13,187
Research and development 26,215 25,173 17,556
Total operating expenses 54,178 46,456 30,743
Operating loss (53,871) (46,456) (30,743)
Change in fair value of warrant liability, net 2,159 15,566 (15,951)
Interest income 19 5 10
Other expense and interest expense (175) 0 0
Net Loss (51,868) (30,885) (46,684)
Common share data:      
Basic and diluted loss per share (in dollars per share) $ (0.85) $ (0.68) $ (1.2)
Weighted average number of basic and diluted common shares outstanding (in shares) 61,275,527 45,236,921 38,991,481
Other comprehensive income (loss):      
Foreign currency translation adjustments 37 0 0
Unrealized loss on securities 0 26 (10)
Other comprehensive income (loss), total 37 26 (10)
Comprehensive loss $ (51,831) $ (30,859) $ (46,694)