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Condensed Consolidated Statements of Cash Flows (Unaudited) (USD $)
In Thousands, unless otherwise specified
 3 Months Ended
Mar. 31, 2013
Mar. 31, 2012
Cash flows from operating activities:    
Net loss $ (12,845) $ (14,889)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock option compensation expense 467 703
Restricted stock compensation expense 197 230
Depreciation expense 298 322
Warrant liability fair value adjustment 2,272 338
Non-cash interest income (2) (3)
Changes in assets and liabilities:    
Increase in prepaid expenses and other current assets (248) (111)
Decrease in accounts receivable 85 0
Increase in inventories (97) 0
Decrease in accounts payable and accrued expenses (764) (772)
Decrease in deferred revenue (300) 0
Net cash used in operating activities (10,937) (14,182)
Cash flows from investing activities:    
Purchase of property, plant, and equipment (34) (572)
Purchase of short-term investments and marketable equity securities 0 (1,743)
Proceeds from maturities of short-term investments 0 2,988
Net cash (used in) provided by investing activities (34) 673
Cash flows from financing activities:    
Net proceeds from sale of stock and exercise of stock options and warrants 30,018 4,782
Net cash provided by financing activities 30,018 4,782
Foreign currency effects on cash 31 0
(Decrease) increase in cash and cash equivalents 19,078 (8,727)
Cash and cash equivalents at beginning of period 23,726 25,777
Cash and cash equivalents at end of period 42,804 17,050
Supplemental non-cash activities:    
Fair value of warrants issued 0 153
Fair value of warrants exercised $ 214 $ 0