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Summary of Significant Accounting Policies (Tables) | 12 Months Ended
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Dec. 31, 2013
Summary of Significant Accounting Policies [Abstract] |
Calculation of net loss and number of shares used to compute basic and diluted earnings per share | The calculation of net loss and the number of shares used to compute basic and diluted earnings per share for the years ended December 31, 2013, 2012 and 2011 are as follows:
(in thousands, except share data) |  | 2013 |  |  | 2012 |  |  | 2011 |
Net loss – basic |  | $ | (30,324 | ) |  | $ | (51,868 | ) |  | $ | (30,885 | )
Adjust for gain on warrant derivative liability |  |  | (1,835 | ) |  |  | — |  |  |  | — |
Net loss - diluted |  |  | (32,159 | ) |  |  | (51,868 | ) |  |  | (30,885 | )
Net loss per share – basic |  |  | (0.30 | ) |  |  | (0.85 | ) |  |  | (0.68 | )
Weighted average shares outstanding – basic |  |  | 100,809,824 |  |  |  | 61,275,527 |  |  |  | 45,236,921 |
Warrant exercises |  |  | 4,294,353 |  |  |  | — |  |  |  | — |
Weighted average shares outstanding – diluted |  |  | 105,104,177 |  |  |  | 61,275,527 |  |  |  | 45,236,921 |
Net loss per share – diluted |  |  | (0.31 | ) |  |  | (0.85 | ) |  |  | (0.68 | )
Shares excluded from the computation of diluted EPS | Shares excluded from the computation of diluted EPS:
|  | 2013 |  |  | 2012 |  |  | 2011 |
Stock options |  |  | 4,035,143 |  |  |  | 4,788,887 |  |  |  | 4,129,749 |
Unvested restricted shares |  |  | 325,722 |  |  |  | 501,468 |  |  |  | 193,532 |
Warrants |  |  | 9,432,000 |  |  |  | 5,642,580 |  |  |  | 2,512,934 |
Total |  |  | 13,792,865 |  |  |  | 10,932,935 |  |  |  | 6,836,215 |

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- Definition Tabular disclosure of securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) in the future that were not included in the computation of diluted EPS because to do so would increase EPS amounts or decrease loss per share amounts for the period presented, by antidilutive securities. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=6371337&loc=d3e3550-109257 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Statement of Financial Accounting Standard (FAS) -Number 128 -Paragraph 40 -Subparagraph c -LegacyDoc This reference is SUPERSEDED by the Accounting Standards Codification effective for interim and annual periods ending after September 15, 2009. This reference is included to help users transition from the previous accounting hierarchy and will be removed from future versions of this taxonomy. + Details
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- Definition Tabular disclosure of an entity's basic and diluted earnings per share calculations. + References No definition available. + Details
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