XML 30 R44.htm IDEA: XBRL DOCUMENT v2.4.0.8
Income Taxes (Details) (USD $)
 12 Months Ended
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Dec. 31, 2009
Provision for income taxes [Abstract]          
Income taxes using U.S. federal statutory rate $ (10,309,000) $ (17,621,000) $ (10,501,000)    
Amortization of Gain on IP Migration 781,000 754,000 0    
State income taxes, net of federal benefit (1,390,000) (4,299,000) (3,418,000)    
Foreign rate differential 2,761,000 3,716,000 52,000    
Valuation allowance 7,683,000 17,561,000 20,563,000 15,000,000 5,900,000
Derivative charge (937,000) (734,000) (5,292,000)    
Stock option exercises and cancellations 1,589,000 310,000 102,000    
Research and development credits (1,090,000) 326,000 (1,633,000)    
Other 912,000 (13,000) 127,000    
Total 0 0 0    
Deferred tax assets [Abstract]          
Employee compensation accruals 4,077,000 6,176,000      
Accrued liabilities 870,000 299,000      
Research tax credits 3,472,000 2,382,000      
Other 79,000 31,000      
Net operating losses 71,874,000 63,765,000      
Total deferred tax assets 80,372,000 72,653,000      
Deferred tax liability [Abstract]          
Total deferred tax liabilities 0 0      
Valuation allowance 80,372,000 72,653,000      
Net deferred tax assets 0 0      
Operating Loss Carryforwards [Line Items]          
Percentage of valuation allowance (in hundredths) 100.00%        
Valuation allowance increased 7,683,000 17,561,000 20,563,000 15,000,000 5,900,000
Tax benefit related to the exercise of non qualified stock options 1,000,000        
Federal [Member]
          
Operating Loss Carryforwards [Line Items]          
Operating loss carryforwards 158,400,000 138,100,000      
Operating loss carryforwards, amount subject to limitations 8,600,000        
Operating loss carryforwards, annual limitation 123,000        
Operating loss carryforwards, net of limitations 152,300,000        
Federal [Member] | Minimum [Member]
          
Operating Loss Carryforwards [Line Items]          
Operating loss carryforwards, expiration dates 2018        
Federal [Member] | Maximum [Member]
          
Operating Loss Carryforwards [Line Items]          
Operating loss carryforwards, expiration dates 2033        
State and city [Member]
          
Operating Loss Carryforwards [Line Items]          
Operating loss carryforwards 268,800,000 231,000,000      
Operating loss carryforwards, expiration dates 2033        
Foreign [Member]
          
Operating Loss Carryforwards [Line Items]          
Operating loss carryforwards $ 19,000,000 $ 17,400,000