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Stockholders' Equity (Tables)
12 Months Ended
Dec. 31, 2014
Stockholders' Equity [Abstract]  
Stock option activity
Options granted under the Plans vest as determined by the Company’s Compensation and Stock Option Committee and expire over varying terms, but not more than ten years from the date of grant. Stock option activity for 2014, 2013, and 2012 is as follows:
   
 
Number of
Options
  
Exercise Price
per Share
  
Weighted Average
Exercise Price
  
Weighted
Average
Remaining
Life (Years)
 
 
 
  
  
  
 
         
Outstanding at January 1, 2012
  
258,069
  
$
19.68-248.64
  
$
81.45
   
6.38
 
Granted
  
75,437
   
22.88-73.60
   
60.80
     
Expired
  
(26,251
)
  
30.08-72.32
   
76.90
     
Forfeited
  
(8,013
)
  
36.16-146.88
   
80.87
     
Outstanding at December 31, 2012
  
299,242
  
$
19.68-248.64
  
$
76.66
   
6.88
 
Granted
  
130,328
   
4.80-34.08
   
17.41
     
Expired
  
(16,874
)
  
6.08-197.44
   
63.50
     
Forfeited
  
(160,538
)
  
19.68-29.92
   
24.47
     
Outstanding at December 31, 2013
  
252,158
  
$
4.80 – 248.64
  
$
57.90
   
7.36
 
Granted
  
165,000
   
1.24 – 2.42
   
1.78
     
Expired
  
(45,666
)
  
4.80 – 110.40
   
47.54
     
Forfeited
  
(89,757
)
  
4.80 – 248.64
   
67.58
     
Outstanding at December 31, 2014
  
281,735
  
$
1.24 – 245.12
  
$
23.63
   
8.83
 
 
Exercisable at December 31, 2014
  
55,634
  
$
21.12 – 245.12
  
$
99.23
   
6.08
 
Assumptions used to determine the fair value of stock options
The estimated fair value of each option award granted was determined on the date of grant using an option pricing model with the following assumptions for option grants during the years ended December 31, 2014, 2013 and 2012: 

 
 
Year Ended December 31,
 
 
 
2014
  
2013
  
2012
 
Weighted average risk-free interest rate
  
1.53
%
  
1.30
%
  
1.11
%
Weighted average expected volatility
  
96.68
%
  
92.31
%
  
79.89
%
Expected volatility
  
95.47%-98.14
%
  
86.16%-97.21
%
  
77.37%-84.81
%
Dividend yield
  
0.00
%
  
0.00
%
  
0.00
%
Weighted average expected option term (in years)
  
4.5
   
5.66
   
6.17
 
Weighted average grant date fair value
 
$
1.78
  
$
17.41
  
$
60.80
 
Non-vested options
A summary of the Company’s non-vested options to purchase shares as of December 31, 2014 and changes during the year ended December 31, 2014 and December 31, 2013 are presented below:

 
 
Non-Vested Options
 
 
 
Number of
Options
  
Weighted
Average
Exercise Price
 
 
 
  
 
Non-vested at January 1, 2013
  
105,143
  
$
74.85
 
Granted
  
130,328
   
17.41
 
Vested
  
(42,893
)
  
85.99
 
Forfeited
  
(73,968
)
  
53.93
 
Non-vested at December 31, 2013
  
118,610
  
$
20.76
 
Granted
  
165,000
   
1.78
 
Vested
  
(46,737
)
  
26.35
 
Forfeited
  
(10,772
)
  
35.92
 
Non-vested at December 31, 2014
  
226,101
  
$
5.03
 
Restricted stock activity
A summary of the Company’s restricted stock activity as of December 31, 2014 and changes during the year ended December 31, 2014 and December 31, 2013 are presented below:
 
 
 
Restricted Stock Activity
 
 
 
Number of Shares
  
Weighted Average
Grant Date Fair
Value
 
 
 
  
 
Non-vested at January 1, 2013
  
31,267
  
$
52.02
 
Granted
  
17,258
   
6.73
 
Vested
  
(19,582
)
  
41.14
 
Forfeited
  
(8,596
)
  
69.16
 
Non-vested at December 31, 2013
  
20,347
  
$
16.84
 
Granted
  
62,504
   
2.60
 
Vested
  
(18,815
)
  
13.60
 
Forfeited
  
(34,237
)
  
3.40
 
Non-vested at December 31, 2014
  
29,799
  
$
4.46
 
Warrant activity
A summary of warrant activity is as follows:
 
 
 
Warrants
  
Exercise Price
per Share
  
Weighted
Average
Exercise
Price
  
Weighted
Average
Remaining Life
(Years)
 
 
 
  
  
  
 
Outstanding at January 1, 2012
  
157,063
  
$
55.04 – 57.60
  
$
56.10
   
1.45
 
Issued
  
407,695
       
26.40
     
Exercised
  
(185,967
)
      
23.84
     
Expired
  
(26,127
)
      
23.84
     
Outstanding at December 31, 2012
  
352,664
  
$
19.20
  
$
19.20
   
2.24
 
Issued
  
589,500
       
7.04
     
Exercised
  
(12,669
)
      
19.20
     
Expired
  
       
     
Outstanding at December 31, 2013
  
929,495
  
$
2.56 – 7.04
  
$
5.40
   
3.51
 
Issued
  
       
     
Exercised
  
(49,139
)
      
2.56
     
Expired
  
(30,218
)
      
2.56
     
Outstanding at December 31, 2014
  
850,138
  
$
1.75 – 7.04
  
$
5.42
   
2.78