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Income Taxes - Significant Components of Deferred Tax Assets (Details) - USD ($) $ in Thousands | Dec. 31, 2015 | Dec. 31, 2014
--- | --- | ---
Deferred tax assets: |  |
Employee compensation accruals | $ 1,279 | $ 1,866
Accrued liabilities | 633 | 1,356
Research tax credits | 3,796 | 3,597
Other | 66 | 45
Net operating losses | 77,906 | 74,359
Total deferred tax assets | 83,680 | 81,223
Deferred tax liabilities: |  |
Total deferred tax liabilities | 0 | 0
Valuation allowance | 83,680 | 81,223
Net deferred tax assets | $ 0 | $ 0

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