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Stockholders' Equity - Stock Option Activity (Details) - $ / shares	12 Months Ended
	Dec. 31, 2015	Dec. 31, 2014	Dec. 31, 2013	Dec. 31, 2012
Stock Options, Number of Options [Roll Forward]
Outstanding, beginning of period (in shares)	281,735	252,158	299,242
Granted (in shares)	524,250	165,000	130,328
Forfeited (in shares)	(49,934)	(89,757)	(160,538)
Expired (in shares)		(45,666)	(16,874)
Outstanding, end of period (in shares)	756,051	281,735	252,158	299,242
Exercisable (in shares)	188,249
Stock Options, Exercise Price per Share [Roll Forward]
Granted (in dollars per share)	$ 1.19
Stock Options, Weighted Average Exercise Price [Roll Forward]
Outstanding, beginning of period (in dollars per share)	23.63	$ 57.90	$ 76.66
Granted (in dollars per share)	1.19	1.78	17.41
Forfeited (in dollars per share)	30.01	67.58	24.47
Expired (in dollars per share)		47.54	63.50
Outstanding, beginning of period (in dollars per share)	7.65	$ 23.63	$ 57.90	$ 76.66
Exercisable (in dollars per share)	$ 26.45
Stock Options, Weighted Average Remaining Life Years [Abstract]
Outstanding	8 years 11 months 12 days	8 years 9 months 29 days	7 years 4 months 10 days	6 years 10 months 17 days
Exercisable	7 years 8 months 1 day
Minimum [Member]
Stock Options, Exercise Price per Share [Roll Forward]
Outstanding, beginning of period (in dollars per share)	$ 1.24	$ 4.80	$ 19.68
Granted (in dollars per share)		1.24	4.80
Forfeited (in dollars per share)	1.19	4.80	19.68
Expired (in dollars per share)		4.80	6.08
Outstanding, end of period (in dollars per share)	1.24	1.24	4.80	$ 19.68
Exercisable (in dollars per share)	1.24
Maximum [Member]
Stock Options, Exercise Price per Share [Roll Forward]
Outstanding, beginning of period (in dollars per share)	245.12	248.64	248.64
Granted (in dollars per share)		2.42	34.08
Forfeited (in dollars per share)	169.60	248.64	29.92
Expired (in dollars per share)		110.40	197.44
Outstanding, end of period (in dollars per share)	245.12	$ 245.12	$ 248.64	$ 248.64
Exercisable (in dollars per share)	$ 245.12

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The number of shares into which fully or partially vested stock options outstanding as of the balance sheet date can be currently converted under the option plan.

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