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Income Taxes - Income tax reconciliation (Details) - USD ($)	12 Months Ended
	Dec. 31, 2015	Dec. 31, 2014	Dec. 31, 2013
Provision for income taxes [Abstract]
Income taxes using U.S federal statutory rate	$ (4,999,000)	$ (5,926,000)	$ (10,309,000)
Amortization of gain on IP migration	767,000	767,000	781,000
State income taxes, net of federal benefit	380,000	2,215,000	(1,390,000)
Foreign rate differential	920,000	1,069,000	2,761,000
Valuation allowance	2,649,000	886,000	7,683,000
Derivative charge	(192,000)	(660,000)	(937,000)
Stock option exercises and cancellations	674,000	1,748,000	1,589,000
Research and development costs	(199,000)	(125,000)	(1,090,000)
Other		26,000	912,000
Total	$ 0	$ 0	$ 0

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The portion of the difference between total income tax expense or benefit as reported in the Income Statement and the expected income tax expense or benefit computed by applying the domestic federal statutory income tax rates to pretax income from continuing operations attributable to derivative costs.

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Amount of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to foreign income tax expense (benefit).

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