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Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2016 | Dec. 31, 2015
Income Statement [Abstract] |  |  |
Product revenue |  | $ 1,992 | $ 1,747
Cost of goods sold |  | (550) | (462)
Gross profit |  | 1,442 | 1,285
Operating expenses: |  |  |
Selling, general and administrative expenses |  | 9,434 | 10,009
Research and development costs |  | 8,448 | 6,486
Total operating expenses |  | 17,882 | 16,495
Operating loss |  | (16,440) | (15,210)
Derivative instrument income |  | 12,780 | 564
Interest income |  | 17 | 9
Other expense and interest expense |  | (14,328) | (67)
Net loss |  | (17,971) | (14,704)
Other comprehensive loss: |  |  |
Foreign currency translation adjustments |  | (33) | (28)
Comprehensive Loss |  | $ (18,004) | $ (14,732)
Common share data: |  |  |
Basic and diluted loss per share | [1] | $ (10.59) | $ (14.56)
Weighted average number of basic and diluted shares outstanding | [1] | 1,696,237 | 1,010,105
[1] | reflects a one-for-sixteen (1:16) reverse stock split effected on July 21, 2016

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