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Description of Business - Additional Information (Details)
12 Months Ended
Dec. 31, 2016
USD ($)
Installment
Dec. 31, 2015
USD ($)
Jun. 13, 2016
USD ($)
Organization Consolidation and Presentation of Financial Statements [Line Items]      
Net loss $ 17,971,000 $ 14,704,000  
Net cash used in operating activities 14,213,000 16,420,000  
Accumulated deficit $ 279,188,000 $ 261,217,000  
Senior Secured Convertible Notes [Member]      
Organization Consolidation and Presentation of Financial Statements [Line Items]      
Debt instrument, original issuance date Jun. 13, 2016    
Debt instrument, principal face amount $ 34,351,000   $ 35,000,000
Debt instrument payable number of equal installments | Installment 14