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Consolidated Statements of Operations and Comprehensive Loss - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Income Statement [Abstract]    
Product revenue $ 1,992 $ 1,747
Cost of goods sold (550) (462)
Gross profit 1,442 1,285
Operating expenses:    
Selling, general and administrative expenses 9,434 10,009
Research and development costs 8,448 6,486
Total operating expenses 17,882 16,495
Operating loss (16,440) (15,210)
Derivative instrument income 12,780 564
Interest income 17 9
Other expense and interest expense (14,328) (67)
Net loss (17,971) (14,704)
Other comprehensive loss:    
Foreign currency translation adjustments (33) (28)
Comprehensive Loss $ (18,004) $ (14,732)
Common share data:    
Basic and diluted loss per share [1] $ (10.59) $ (14.56)
Weighted average number of basic and diluted shares outstanding [1] 1,696,237 1,010,105
[1] reflects a one-for-sixteen (1:16) reverse stock split effected on July 21, 2016