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Stockholders' Equity - Stock and Warrant Issuances - Additional Information (Details) - USD ($)
 1 Months Ended 12 Months Ended
Oct. 31, 2016
Jul. 31, 2015
Feb. 28, 2015
Oct. 31, 2013
Dec. 31, 2016
Jun. 30, 2016
Jun. 13, 2016
Dec. 31, 2015
Oct. 20, 2015
Dec. 31, 2014
Stockholders Equity Note [Line Items]                    
Sale of common stock, net of expenses (in shares) 425,000 600,000 153,750 81,875            
Proceeds from issuance of private placement $ 1,200,000   $ 2,600,000 $ 7,500,000            
Net proceeds from issuance of private placement $ 1,100,000   $ 2,500,000 $ 6,900,000            
Number of warrants outstanding (in shares)         7,216,020     1,128,688   53,134
Sale of units to underwriter   600,000                
Proceeds of common stock issued, net of related expenses   $ 6,000,000                
Maximum [Member]                    
Stockholders Equity Note [Line Items]                    
Warrants exercisable per share price (in dollars per share)         $ 112.64     $ 112.64   $ 112.64
Maximum offering and selling of stock and securities that entity make to raise capital                 $ 77,400,000  
Entity public float pursuant to SEC regulations                 $ 75,000,000  
Senior Secured Convertible Notes [Member]                    
Stockholders Equity Note [Line Items]                    
Debt instrument, principal face amount         $ 34,351,000   $ 35,000,000      
Series A Common Stock Warrants [Member]                    
Stockholders Equity Note [Line Items]                    
Warrants exercisable per share price (in dollars per share)         $ 1.61          
Number of warrants outstanding (in shares)         300,000          
Warrants exercised (in shares)         300,000          
Net proceeds from exercise of warrants         $ 400,000          
Number of warrants converted   400,000           100,000    
Gross proceeds from underwriting offering   $ 7,000,000                
Warrants expiry period         5 years          
Series B Common Stock Warrants [Member]                    
Stockholders Equity Note [Line Items]                    
Warrants exercised (in shares)         100,000          
Net proceeds from exercise of warrants         $ 800,000          
Number of warrants converted   600,000                
Remaining outstanding warrants expired         400,000          
Warrants expiration date         Jan. 29, 2016          
Series A and B Common Stock Warrants [Member]                    
Stockholders Equity Note [Line Items]                    
Value of warrants issued   $ 3,400,000                
2013 Warrants [Member]                    
Stockholders Equity Note [Line Items]                    
Warrants issued (in shares)       37,000            
Value of warrants issued       $ 1,900,000            
Warrants exercisable per share price (in dollars per share)         $ 112.64          
Number of warrants outstanding (in shares)         36,848          
Term period for warrants         5 years          
February 2015 Warrants [Member]                    
Stockholders Equity Note [Line Items]                    
Warrants issued (in shares)     69,000              
Value of warrants issued     $ 800,000              
Warrants exercisable per share price (in dollars per share)         $ 1.61          
Number of warrants outstanding (in shares)         30,238          
Term period for warrants         5 years          
Warrants exercised (in shares)         40,000          
Net proceeds from exercise of warrants         $ 100,000          
Series C Warrants [Member]                    
Stockholders Equity Note [Line Items]                    
Value of warrants issued           $ 27,800,000        
Warrants exercisable per share price (in dollars per share)         $ 4.83          
Number of warrants outstanding (in shares)         6,800,000          
Percentage of increased number of warrant shares issuable upon exercise         75.00%          
Description of warrant issued upon exercise         On December 31, 2017, the number of Warrant Shares issuable upon exercise of the Series C Warrants will be increased by such number of Warrant Shares equal to 75% of the difference of (i) the quotient of (A) the product of (x) the exercise price as of the date of issuance (as adjusted for certain events) multiplied by (y) the number of Warrant Shares as of the date of issuance (as adjusted for certain events), divided by (B) the volume-weighted average price of the Common Stock on the maturity date, less (ii) the number of Warrant Shares as of the date of issuance (as adjusted for certain events).          
Warrants holding period         1 year          
Warrants exercisable period         5 years          
Series C Warrants [Member] | Senior Secured Convertible Notes [Member]                    
Stockholders Equity Note [Line Items]                    
Number of warrants converted           6,800,000        
Debt instrument, principal face amount           $ 35,000,000        
October 2016 Warrants [Member]                    
Stockholders Equity Note [Line Items]                    
Warrants issued (in shares) 148,750                  
Value of warrants issued $ 300,000                  
Warrants exercisable per share price (in dollars per share)         $ 1.61          
Number of warrants outstanding (in shares)         78,750          
Term period for warrants         5 years          
Warrants exercised (in shares)         70,000          
Net proceeds from exercise of warrants         $ 100,000