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Description of Business - Additional Information (Details) - USD ($) $ in Thousands | 3 Months Ended | 12 Months Ended
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Dec. 31, 2017 | Sep. 30, 2017 | Jun. 30, 2017 | Mar. 31, 2017 | Dec. 31, 2016 | Sep. 30, 2016 | Jun. 30, 2016 | Mar. 31, 2016 | Dec. 31, 2017 | Dec. 31, 2016 | Dec. 31, 2015
Organization Consolidation And Presentation Of Financial Statements [Abstract] |  |  |  |  |  |  |  |  |  |  |
Net loss | $ 19,246 | $ 12,596 | $ 1,943 | $ 11,332 | $ 8,486 | $ 1,004 | $ 6,667 | $ 1,813 | $ 45,117 | $ 17,971 | $ 14,704
Net cash used in operating activities |  |  |  |  |  |  |  |  | 15,398 | 14,213 | $ 16,420
Accumulated deficit | $ 324,832 |  |  |  | $ 279,188 |  |  |  | $ 324,832 | $ 279,188 |

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- Definition Amount of cash inflow (outflow) from operating activities, excluding discontinued operations. Operating activity cash flows include transactions, adjustments, and changes in value not defined as investing or financing activities. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 24 -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3521-108585 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3602-108585 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 25 -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3536-108585 + Details
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