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Consolidated Statements of Cash Flows - USD ($) | 12 Months Ended
--- | ---
Dec. 31, 2017 | Dec. 31, 2016 | Dec. 31, 2015
Cash flows from operating activities: |  |  |
Net loss | $ (45,117,000) | $ (17,971,000) | $ (14,704,000)
Adjustments to reconcile net loss to net cash used in operating activities: |  |  |
Stock option compensation expense | 50,000 | 161,000 | 349,000
Restricted stock compensation expense | 79,000 | 266,000 | 308,000
Depreciation expense | 310,000 | 305,000 | 617,000
Loss on disposal of equipment | 18,000 | 1,000 | 15,000
Warrant liability fair value adjustment | (15,103,000) | (12,780,000) | (564,000)
Gain on warrant extinguishment | (9,613,000) | 0 | 0
Non-cash interest income | (1,000) | (1,000) | (1,000)
Debt discount and deferred finance costs amortization | 21,544,000 | 14,268,000 | 0
Loss on debt settlements and extinguishments | 29,924,000 | 0 | 0
Changes in assets and liabilities: |  |  |
Decrease in prepaid expenses and other assets | 7,000 | 260,000 | 9,000
(Increase) decrease in accounts receivable | 108,000 | (138,000) | (52,000)
Decrease (increase) in inventories | (543,000) | 95,000 | (420,000)
Increase (decrease) in accounts payable and accrued expenses | 3,180,000 | 1,507,000 | (1,757,000)
Increase (decrease) in deferred revenue | (32,000) | 30,000 | 0
Decrease in other non-current liabilities | (209,000) | (216,000) | (220,000)
Net cash used in operating activities | (15,398,000) | (14,213,000) | (16,420,000)
Cash flows from investing activities: |  |  |
Purchase of property, plant and equipment | (524,000) | (258,000) | (170,000)
Increase in restricted cash | 0 | (1,087,000) | 0
Proceeds from sales of property, plant and equipment | 0 | 0 | 180,000
Net cash (used in) provided by investing activities | (524,000) | (1,345,000) | 10,000
Cash flows from financing activities: |  |  |
Increase in restricted cash | 0 | (26,200,000) | 0
Net proceeds from the release of restricted cash | 13,120,000 | 0 | 0
Net proceeds from sale of Series B and Series C preferred shares | 2,310,000 | 0 | 0
Net proceeds from convertible note debt financing | 0 | 31,226,000 | 0
Net proceeds from sale of stock and exercise of warrants | 15,000 | 2,383,000 | 8,655,000
Net cash provided by financing activities | 15,445,000 | 7,409,000 | 8,655,000
Fx effect on cash | 67,000 | (49,000) | (107,000)
Increase (decrease) in cash and cash equivalents | (410,000) | (8,198,000) | (7,862,000)
Cash and cash equivalents at beginning of period | 4,409,000 | 12,607,000 | 20,469,000
Cash and cash equivalents at end of period | 3,999,000 | 4,409,000 | 12,607,000
Supplemental non-cash activities: |  |  |
Conversion of convertible notes | 40,121,000 | 649,000 | 0
Fair value of warrants issued | 16,953,000 | 28,472,000 | 4,247,000
Cashless exercise of warrants | 2,537,000 | 0 | 0
Deemed dividend | 527,000 | 0 | 0
Fair value of warrants exercised for cash | 19,000 | 726,000 | 123,000
Series A and Series B Preferred Shares [Member] |  |  |
Cash flows from financing activities: |  |  |
Release of restricted cash for redemption of preferred shares | 2,360,000 | 0 | 0
Cash paid to redeem preferred shares | (2,360,000) | 0 | 0
Series C Preferred Shares [Member] |  |  |
Cash flows from financing activities: |  |  |
Release of restricted cash for redemption of preferred shares | 590,000 | 0 | 0
Cash paid to redeem preferred shares | (590,000) | 0 | 0
Series C Warrants [Member] |  |  |
Cash flows from financing activities: |  |  |
Release of restricted cash for extinguishment of Series C Warrants | 7,876,000 | 0 | 0
Cash paid to extinguish of Series C Warrants | $ (7,876,000) | $ 0 | $ 0

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- Definition The cash outflow associated with the acquisition of long-lived, physical assets that are used in the normal conduct of business to produce goods and services and not intended for resale; includes cash outflows to pay for construction of self-constructed assets. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 13 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3213-108585 + Details
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- Definition The cash inflow from the issuance of a long-term debt instrument which can be exchanged for a specified amount of another security, typically the entity's common stock, at the option of the issuer or the holder. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 14 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3255-108585 + Details
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- Definition Proceeds from issuance of capital stock which provides for a specific dividend that is paid to the shareholders before any dividends to common stockholders and which takes precedence over common stockholders in the event of liquidation. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 14 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3255-108585 + Details
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- Definition The cash inflow from the issuance of common stock, preferred stock, treasury stock, stock options, and other types of equity. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 14 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3255-108585 + Details
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- Definition The net cash inflow or outflow from cash and cash items that are not available for withdrawal or usage. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 14 -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3255-108585 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 15 -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3291-108585 + Details
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- Definition The cash inflow from the sale of long-lived, physical assets that are used in the normal conduct of business to produce goods and services and not intended for resale. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 12 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3179-108585 + Details
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- Definition The noncash expense that represents the cost of restricted stock or unit distributed to employees as compensation. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3602-108585 + Details
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- Definition The noncash expense that accounts for the value of stock or unit options distributed to employees as compensation. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3602-108585 + Details
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