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Fair Value Measurements (Tables) | 9 Months Ended | 12 Months Ended
--- | --- | ---
Sep. 30, 2017 | Dec. 31, 2016
Fair Value Disclosures [Abstract] |  |
Schedule of fair value of the warrants | The fair value of the Warrants at September 30, 2017 was determined by using option pricing models with the following assumptions:
|  | October 2016 Warrants |  |  | July 2015 Series A Warrants |  |  | February 2015 Warrants |  |  | October 2013 Warrants |
Expected volatility |  |  | 142.46 | % |  |  | 165.32 | % |  |  | 181.24 | % |  |  | 227.68 | %
Risk-free interest rates |  |  | 1.77 | % |  |  | 1.59 | % |  |  | 1.53 | % |  |  | 1.33 | %
Expected life (in years) |  |  | 4.02 |  |  |  | 2.81 |  |  |  | 2.38 |  |  |  | 1.08 |
| The fair value of the Warrants at December 31, 2016 was determined by using option pricing models assuming the following:
|  | October |  |  | June 2016 |  |  | July 2015 |  |  | February |  |  | October |
|  | 2016 |  |  | Series C |  |  | Series A |  |  | 2015 |  |  | 2013 |
|  | Warrants |  |  | Warrants |  |  | Warrants |  |  | Warrants |  |  | Warrants |
Expected volatility |  |  | 95.03 | % |  |  | 94.19 | % |  |  | 95.51 | % |  |  | 95.52 | % |  |  | 152.70 | %
Risk free interest rates |  |  | 1.93 | % |  |  | 2.01 | % |  |  | 1.59 | % |  |  | 1.47 | % |  |  | 1.20 | %
Expected life (in years) |  |  | 4.80 |  |  |  | 5.50 |  |  |  | 3.60 |  |  |  | 3.10 |  |  |  | 1.80 |
Assets and liabilities measured at fair value on a recurring basis | The table below presents the Company’s assets and liabilities measured at fair value on a recurring basis as of September 30, 2017, aggregated by the level in the fair value hierarchy within which those measurements fall in accordance with ASC 820.
|  | Assets and Liabilities Measured at Fair Value on a Recurring Basis |
|  |  |  |  |  |  |  |  |  |  | Balance at |
|  |  |  |  |  |  |  |  |  |  | September 30, |
(in thousands) |  | Level 1 |  |  | Level 2 |  |  | Level 3 |  |  | 2017 |
Liabilities |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Derivative instrument liabilities |  | $ | — |  |  | $ | — |  |  | $ | 16 |  |  | $ | 16 |
| The table below presents the Company’s assets and liabilities measured at fair value on a recurring basis as of December 31, 2016 and 2015, aggregated by the level in the fair value hierarchy within which those measurements fall. Assets and Liabilities Measured at Fair Value on a Recurring Basis
|  | Assets and Liabilities Measured at Fair Value on a Recurring Basis |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | Balance at |
|  | Level 1 |  |  | Level 2 |  |  | Level 3 |  |  | December 31, |
(in thousands) |  | 2016 |  |  | 2015 |  |  | 2016 |  |  | 2015 |  |  | 2016 |  |  | 2015 |  |  | 2016 |  |  | 2015 |
Liabilities |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Derivative instrument liabilities |  | $ | — |  |  | $ | — |  |  | $ | — |  |  | $ | — |  |  | $ | 18,751 |  |  | $ | 3,785 |  |  | $ | 18,751 |  |  | $ | 3,785 |
Fair value measurements using significant unobservable inputs | The table below presents the activity within Level 3 of the fair value hierarchy for the nine months ended September 30, 2017: Fair Value Measurements Using Significant Unobservable Inputs (Level 3)
(in thousands) |  | Warrant Liability |
Balance at December 31, 2016 |  | $ | 18,751 |
Total change in the liability included in earnings |  |  | (1,227 | )
Extinguishment of convertible note warrant |  |  | (17,489 | )
Fair value of warrants issued |  |  | — |
Fair value of warrants exercised |  |  | (19 | )
Balance at September 30, 2017 |  | $ | 16 |
| Fair Value Measurements Using Significant Unobservable Inputs (Level 3)
(in thousands) |  | Warrant Liability |
Balance at January 1, 2015 |  | $ | 225 |
Total change in the liability included in earnings |  |  | (564 | )
Fair value of warrants issued |  |  | 4,247 |
Fair value of warrants exercised |  |  | (123 | )
Balance at December 31, 2015 |  |  | 3,785 |
Total change in the liability included in earnings |  |  | (12,780 | )
Fair value of warrants issued |  |  | 28,472 |
Fair value of warrants exercised |  |  | (726 | )
Balance at December 31, 2016 |  | $ | 18,751 |

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- Definition Tabular disclosure of the fair value measurement of liabilities using significant unobservable inputs (Level 3), a reconciliation of the beginning and ending balances, separately presenting changes attributable to the following: (1) total gains or losses for the period (realized and unrealized), segregating those gains or losses included in earnings (or changes in net assets), and gains or losses recognized in other comprehensive income (loss) and a description of where those gains or losses included in earnings (or changes in net assets) are reported in the statement of income (or activities); (2) purchases, sales, issues, and settlements (each type disclosed separately); and (3) transfers in and transfers out of Level 3 (for example, transfers due to changes in the observability of significant inputs) by class of liability. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 820 -SubTopic 10 -Section 50 -Paragraph 3 -URI http://asc.fasb.org/extlink&oid=66048111&loc=d3e19279-110258 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 820 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=66048111&loc=d3e19207-110258 + Details
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- Definition Tabular disclosure of all information related to the key inputs and assumptions (including, at a minimum, but not limited to, and if applicable, quantitative information about discount rates, expected prepayments including the expected weighted-average life of prepayable financial assets, and anticipated credit losses) used in measuring the fair value of assets or liabilities that relate to the transferor's continuing involvement with transferred financial assets, as of the balance sheet date. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 860 -SubTopic 20 -Section 50 -Paragraph 4 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=82924980&loc=d3e107314-111719 + Details
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- Definition Tabular disclosure of assets and liabilities, including [financial] instruments measured at fair value that are classified in stockholders' equity, if any, that are measured at fair value on a recurring basis. The disclosures contemplated herein include the fair value measurements at the reporting date by the level within the fair value hierarchy in which the fair value measurements in their entirety fall, segregating fair value measurements using quoted prices in active markets for identical assets (Level 1), significant other observable inputs (Level 2), and significant unobservable inputs (Level 3). + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 820 -SubTopic 10 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=66048111&loc=d3e19190-110258 + Details
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