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Income Taxes - Significant Components of Deferred Tax Assets (Detail) - USD ($) $ in Thousands | Dec. 31, 2016 | Dec. 31, 2015 | Dec. 31, 2014
--- | --- | --- | ---
Deferred tax assets: |  |  |
Employee compensation accruals | $ 1,386 | $ 1,279 |
Accrued liabilities | 343 | 633 |
Research tax credits | 22 | 3,796 |
Other | 55 | 66 |
Net operating losses | 6,194 | 77,906 |
Total deferred tax assets | 8,000 | 83,680 |
Deferred tax liabilities: |  |  |
Beneficial conversion feature | 906 |  |
Total deferred tax liabilities | 906 |  |
Valuation allowance | 7,094 | 83,680 | $ 81,223
Net deferred tax assets | $ 0 | $ 0 |

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