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Stockholders' Equity (Tables)
12 Months Ended
Dec. 31, 2016
Stockholders Equity Note Abstract  
Stock option activity

Stock option activity for 2016 and 2015 is as follows:

 

     Stock Option Activity under the Plans  
                          Weighted Average  
            Exercise Price per      Weighted Average      Remaining Life  
     Stock Options      Share      Exercise Price      (Years)  

Outstanding at December 31, 2014

     17,577      $ 19.84 - $3,921.92      $ 378.08        8.83  

Granted

     32,765        19.04        19.04     

Forfeited

     (3,121      19.04 - 2,713.60        480.16     
  

 

 

          

Outstanding at December 31, 2015

     47,221        19.04 - 3,921.92      $ 122.40        8.95  
  

 

 

          

Granted

     —          —          —       

Forfeited

     (5,865    $ 19.04 - $545.28        23.95     
  

 

 

          

Outstanding at December 31, 2016

     41,356      $ 19.84 - $3,788.80      $ 135.77        7.90  
  

 

 

          

Exercisable at December 31, 2016

     26,774      $ 19.04 - $3,788.80      $ 199.31        7.63  
  

 

 

          
Assumptions used to determine estimated fair value of stock options granted

the following assumptions for option grants during the year ended December 31, 2015. There were no option grants during the year ended December 31, 2016:

 

     Year ended
December 31, 2015
 

Weighted average risk-free interest rates

     1.82

Weighted average expected volatility

     97.70

Dividend yield

     —    

Weighted average expected option term (in years)

     5.15  

Weighted average grant date fair value

   $ 0.89  
Summary of non-vested options

A summary of the Company’s non-vested options to purchase shares as of December 31, 2016 and changes during the year ended December 31, 2016 and December 31, 2015 are presented below:

 

     Non-Vested Options  
            Weighted  
     Number of      Average  
     Options      Exercise Price  

Non-vested at January 1, 2015

     14,116      $ 332.16  

Granted

     32,765        28.48  

Vested

     (9,994      421.60  

Forfeited

     (1,416      574.72  
  

 

 

    

Non-vested at December 31, 2015

     35,471      $ 22.55  

Granted

     —          —    

Vested

     (15,671      26.85  

Forfeited

     (5,218      19.23  
  

 

 

    

Non-vested at December 31, 2016

     14,582      $ 19.11  
  

 

 

    
Summary of restricted stock activity

A summary of the Company’s restricted stock activity as of December 31, 2016 and changes during the year ended December 31, 2016 and December 31, 2015 are presented below:

 

     Restricted Stock Activity  
            Weighted  
            Average  
     Number      Grant Date  
     of Shares      Fair Value  

Non-vested at January 1, 2015

     1,857      $ 269.44  

Granted

     36,000        41.60  

Vested

     (1,854      217.60  

Forfeited

     (8      54.40  
  

 

 

    

Non-vested at December 31, 2015

     35,995      $ 19.04  

Granted

     4,687        4.32  

Vested

     (19,189      15.44  

Forfeited

     (2,500      19.04  
  

 

 

    

Non-vested at December 31, 2016

     18,993      $ 19.04  
  

 

 

    
Summary of warrant activity

The Company issued warrants as part of its offerings in 2013, 2015, and 2016, as well as part of its issuance of convertible notes in 2016. A summary of warrant activity is as follows:

 

                   Weighted      Weighted  
                   Average      Average  
            Exercise Price      Exercise      Remaining  
     Warrants      per Share      Price      Life (Years)  

Outstanding at January 1, 2014

     53,134        28.00-112.64      $ 86.69        2.78  

Issued

     1,091,844           12.80     

Exercised

     (13,457         13.12     

Expired

     (2,833         13.12     
  

 

 

          

Outstanding at December 31, 2015

     1,128,688        11.84-112.64      $ 16.02        2.16  

Issued

     7,031,929           4.80     

Exercised

     (499,633         2.75     

Expired

     (444,964         5.68     
  

 

 

          

Outstanding at December 31, 2016

     7,216,020        1.61-112.64      $ 5.20        5.59