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Accrued Expenses (Tables) | 3 Months Ended | 12 Months Ended
--- | --- | ---
Mar. 31, 2018 | Dec. 31, 2017
Payables and Accruals [Abstract] |  |
Schedule of accrued expenses | Accrued expenses consist of the following:
(in thousands) |  | March 31, 2018 |  |  | December 31, 2017 |
Compensation, excluding taxes |  | $ | 738 |  |  | $ | 1,124 |
Clinical trial expenses |  |  | 1,603 |  |  |  | 869 |
Professional fees |  |  | 95 |  |  |  | 221 |
Short-term portion of lease restructuring |  |  | 197 |  |  |  | 209 |
Other1 |  |  | 893 |  |  |  | 985 |
Total accrued expenses |  | $ | 3,526 |  |  | $ | 3,408 |
1 | Other consists of various accrued expenses, with no individual item accounting for more than 5% of current liabilities at March 31, 2018 and December 31, 2017.
| Current accrued expenses include the following:
(in thousands) |  | December 31, 2017 |  |  | December 31, 2016 |
Clinical trial expenses |  | $ | 869 |  |  | $ | 1,365 |
Compensation, excluding taxes |  |  | 1,124 |  |  |  | 933 |
Professional fees |  |  | 221 |  |  |  | 286 |
Short-term portion of lease restructuring |  |  | 209 |  |  |  | 216 |
Other1 |  |  | 985 |  |  |  | 607 |
Total accrued expenses |  | $ | 3,408 |  |  | $ | 3,407 |

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