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Quarterly Financial Data (Unaudited) (Detail) - USD ($) $ / shares in Units, $ in Thousands | 3 Months Ended | 12 Months Ended
--- | --- | ---
Mar. 31, 2018 | Dec. 31, 2017 | Sep. 30, 2017 | Jun. 30, 2017 | Mar. 31, 2017 | Dec. 31, 2016 | Sep. 30, 2016 | Jun. 30, 2016 | Mar. 31, 2016 | Dec. 31, 2017 | Dec. 31, 2016 | Dec. 31, 2015
Quarterly Financial Information Disclosure [Abstract] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue | $ 702 |  | $ 704 | $ 684 | $ 584 | $ 743 |  | $ 676 | $ 435 | $ 511 | $ 370 | $ 2,715 | $ 1,992 | $ 1,747
Costs and expenses | 8,058 |  | 5,254 | 5,139 | 5,050 | 4,736 |  | 4,882 | 5,047 | 4,232 | 3,721 | 20,179 | 17,882 | 16,495
Operating loss | (7,503) |  | (4,725) | (4,627) | (4,601) | (4,212) |  | (4,383) | (4,724) | (3,871) | (3,462) | (18,165) | (16,440) | (15,210)
Net loss | $ 7,187 |  | $ (19,246) | $ (12,596) | $ (1,943) | $ (11,332) |  | $ (8,486) | $ (1,004) | $ (6,667) | $ (1,813) | $ (45,117) | $ (17,971) | $ (14,704)
Basic loss per share | $ 10.91 | [1] | $ 375 | $ 4,680 | $ 1,750 | $ (45,695.00) | [1] | $ 646,010 | $ 115,495 | $ 771,750 | $ 218,750 |  |  |
Scenario, Previously Reported [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Quarterly Financial Information Disclosure [Abstract] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Basic loss per share |  |  |  |  |  | $ 43,750 |  |  |  |  |  |  |  |
[1] | reflects a one-for-three hundred and fifty (1:350) reverse stock split effected on November 6, 2017 and a one-for-five hundred (1:500) reverse stock split effected on May 2, 2018.

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