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Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($)
$ in Thousands
3 Months Ended 12 Months Ended
Mar. 31, 2018
Mar. 31, 2017
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Income Statement [Abstract]          
Revenue $ 702 $ 743 $ 2,715 $ 1,992 $ 1,747
Cost of goods sold 147 219 701 550 462
Gross profit 555 524 2,014 1,442 1,285
Operating expenses:          
Selling, general and administrative 2,366 2,415 9,684 9,434 10,009
Research and development 5,692 2,321 10,495 8,448 6,486
Total operating expenses 8,058 4,736 20,179 17,882 16,495
Operating loss (7,503) (4,212) (18,165) (16,440) (15,210)
Change in fair value of the warrant liability, net 14,697 1,238 15,103 12,780 564
Gain on warrant extinguishment     9,613 0 0
Loss on debt settlements and extinguishments     (29,924) 0 0
Interest expense (2) (8,366) (21,703) (14,328) (67)
Other (expense) income (5) 8 (41) 17 9
Net income (loss) 7,187 (11,332) (45,117) (17,971) (14,704)
Other comprehensive income (loss):          
Foreign currency translation adjustments (34) (22) 83 (33) (28)
Comprehensive income (loss) $ 7,153 $ (11,354) $ (45,034) $ (18,004) $ (14,732)
Common share data:          
Basic and diluted loss per share [1]     $ (3,250) $ (1,853,500) $ (2,548,000)
Basic income (loss) per common share [2] $ 10.91 $ (45,695.00)      
Diluted income (loss) per share [2] $ 10.91 $ (45,695.00)      
Weighted average number of basic shares outstanding [2] 658,893 248      
Weighted average number of diluted shares outstanding [2] 658,893 248      
Weighted average number of basic and diluted shares outstanding [1]     14,039 10 6
[1] reflects a one-for-sixteen (1:16) reverse stock split effected on July 21, 2016, a one-for-three hundred and fifty (1:350) reverse stock split effected on November 6, 2017 and a one-for-five hundred (1:500) reverse stock split effected on May 2, 2018.
[2] reflects a one-for-three hundred and fifty (1:350) reverse stock split effected on November 6, 2017 and a one-for-five hundred (1:500) reverse stock split effected on May 2, 2018.