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General - Additional Information (Detail) $ / shares in Units, $ in Thousands				3 Months Ended									12 Months Ended
	May 02, 2018 $ / shares shares	Nov. 06, 2017 $ / shares shares	Jul. 21, 2016 $ / shares shares	Mar. 31, 2018 USD ($) Contract $ / shares	Dec. 31, 2017 USD ($) $ / shares	Sep. 30, 2017 USD ($)	Jun. 30, 2017 USD ($)	Mar. 31, 2017 USD ($)	Dec. 31, 2016 USD ($) $ / shares	Sep. 30, 2016 USD ($)	Jun. 30, 2016 USD ($)	Mar. 31, 2016 USD ($)	Dec. 31, 2017 USD ($) $ / shares	Dec. 31, 2016 USD ($) $ / shares	Dec. 31, 2015 USD ($)
Class Of Stock [Line Items]
Net loss | $				$ (7,187)	$ 19,246	$ 12,596	$ 1,943	$ 11,332	$ 8,486	$ 1,004	$ 6,667	$ 1,813	$ 45,117	$ 17,971	$ 14,704
Net cash used in operating activities | $													15,398
Accumulated deficit | $				$ 317,645	$ 324,832				$ 279,188				$ 324,832	$ 279,188
Reverse stock split		1:350
Reverse stock split ratio		0.0029	0.0625
Number of fractional shares were issued in connected with the reverse stock split | shares			0
Common stock, par value (in dollars per share) | $ / shares			$ 0.01	$ 0.01	$ 0.01				$ 0.01				$ 0.01	$ 0.01
Number of distribution contracts with Turkish distributor | Contract				1
Subsequent Event [Member]
Class Of Stock [Line Items]
Reverse stock split	1:500
Reverse stock split ratio	0.002
OTCQB [Member]
Class Of Stock [Line Items]
Reverse stock split ratio		0.0029
Number of fractional shares were issued in connected with the reverse stock split | shares		0
Common stock, par value (in dollars per share) | $ / shares		$ 0.01
OTCQB [Member] | Subsequent Event [Member]
Class Of Stock [Line Items]
Reverse stock split	1:500
Reverse stock split ratio	0.0020
Number of fractional shares were issued in connected with the reverse stock split | shares	0
Common stock, par value (in dollars per share) | $ / shares	$ 0.01

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