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Fair Value Measurements - Schedule of Fair Value of Warrants (Detail)
3 Months Ended 12 Months Ended
Mar. 31, 2018
Dec. 31, 2017
Minimum [Member]    
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]    
Expected volatility (in hundredths) 122.68% 130.88%
Risk-free interest rates (in hundredths) 1.95% 1.68%
Expected life (in years) 6 months 29 days 9 months 25 days
Maximum [Member]    
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]    
Expected volatility (in hundredths) 291.61% 266.92%
Risk-free interest rates (in hundredths) 2.63% 2.06%
Expected life (in years) 5 years 10 months 13 days 4 years 10 months 17 days
November 2017 Warrants [Member]    
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]    
Expected volatility (in hundredths)   217.39%
Risk-free interest rates (in hundredths)   1.98%
Expected life (in years)   4 years 10 months 17 days
October 2016 Warrants [Member]    
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]    
Expected volatility (in hundredths)   130.88%
Risk-free interest rates (in hundredths)   2.06%
Expected life (in years)   3 years 9 months 3 days
July 2015 Series A Warrants [Member]    
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]    
Expected volatility (in hundredths)   161.87%
Risk-free interest rates (in hundredths)   1.94%
Expected life (in years)   2 years 6 months 21 days
February 2015 Warrants [Member]    
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]    
Expected volatility (in hundredths)   169.95%
Risk-free interest rates (in hundredths)   1.90%
Expected life (in years)   2 years 1 month 16 days
October 2013 Warrants [Member]    
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]    
Expected volatility (in hundredths)   266.92%
Risk-free interest rates (in hundredths)   1.68%
Expected life (in years)   9 months 25 days