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Summary of Significant Accounting Policies - Summary of Computation of Basic and Diluted Earnings Per Share (Details) - USD ($) $ / shares in Units, $ in Thousands | 3 Months Ended | 12 Months Ended
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Dec. 31, 2017 | Sep. 30, 2017 | Jun. 30, 2017 | Mar. 31, 2017 | Dec. 31, 2016 | Sep. 30, 2016 | Jun. 30, 2016 | Mar. 31, 2016 | Dec. 31, 2017 | Dec. 31, 2016 | Dec. 31, 2015
Calculation of net loss and the number of shares used to compute basic and diluted earnings per share [Abstract] |  |  |  |  |  |  |  |  |  |  |  |
Net loss |  | $ (19,246) | $ (12,596) | $ (1,943) | $ (11,332) | $ (8,486) | $ (1,004) | $ (6,667) | $ (1,813) | $ (45,117) | $ (17,971) | $ (14,704)
Preferred stock dividends |  |  |  |  |  |  |  |  |  | (527) |  |
Net loss, adjusted |  |  |  |  |  |  |  |  |  | $ (45,644) | $ (17,971) | $ (14,704)
Net loss per share – basic and diluted | [1] |  |  |  |  |  |  |  |  | $ (6.50) | $ (3,707) | $ (5,096)
Weighted average shares outstanding – basic and diluted | [1] |  |  |  |  |  |  |  |  | 7,019,316 | 4,847 | 2,887
[1] | reflects a one-for-sixteen (1:16) reverse stock split effected on July 21, 2016 and a one-for-three hundred and fifty (1:350) reverse stock split effected on November 6, 2017.

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- Definition Amount of paid and unpaid preferred stock dividends declared with the form of settlement in cash. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 942 -SubTopic 405 -Section 45 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=6957935&loc=d3e64057-112817 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 505 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.3-04) -URI http://asc.fasb.org/extlink&oid=27012166&loc=d3e187085-122770 + Details
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- Definition The amount of net income or loss for the period per each share in instances when basic and diluted earnings per share are the same amount and reported as a single line item on the face of the financial statements. Basic earnings per share is the amount of net income or loss for the period per each share of common stock or unit outstanding during the reporting period. Diluted earnings per share includes the amount of net income or loss for the period available to each share of common stock or common unit outstanding during the reporting period and to each share or unit that would have been outstanding assuming the issuance of common shares or units for all dilutive potential common shares or units outstanding during the reporting period. + References No definition available. + Details
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