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Subsequent Events - Additional Information (Details) $ / shares in Units, $ in Millions | Feb. 26, 2018 shares | Feb. 09, 2018 USD ($) $ / shares shares | Nov. 06, 2017 | Jul. 21, 2016 | Jul. 19, 2016 shares | Jan. 25, 2018 shares | Dec. 31, 2017 $ / shares shares | Dec. 31, 2016 $ / shares shares | Jul. 18, 2016 shares | Dec. 31, 2015 $ / shares | Dec. 31, 2014 $ / shares
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Subsequent Event [Line Items] |  |  |  |  |  |  |  |  |  |  |
Common stock, shares issued (in shares) |  |  |  |  |  |  | 114,055,137 | 11,805 |  |  |
Common stock, shares outstanding (in shares) |  |  |  |  |  |  | 114,054,851 | 11,750 |  |  |
Common stock, shares authorized (in shares) |  |  |  |  | 500,000,000 |  | 500,000,000 | 500,000,000 | 170,000,000 |  |
Reverse stock split ratio |  |  | 0.0029 | 0.0625 |  |  |  |  |  |  |
Minimum [Member] |  |  |  |  |  |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |  |  |  |  |  |
Warrants exercisable per share price (in dollars per share) | $ / shares |  |  |  |  |  |  | $ 2.45 | $ 563.50 |  | $ 4,144 | $ 9,800
Reverse stock split ratio |  |  |  |  | 0.1 |  |  |  |  |  |
Maximum [Member] |  |  |  |  |  |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |  |  |  |  |  |
Warrants exercisable per share price (in dollars per share) | $ / shares |  |  |  |  |  |  | $ 39,424 | $ 39,424 |  | $ 39,424 | $ 39,424
Reverse stock split ratio |  |  |  |  | 0.05 |  |  |  |  |  |
Subsequent Event [Member] | Minimum [Member] | Board of Directors [Member] |  |  |  |  |  |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |  |  |  |  |  |
Common stock, shares authorized (in shares) | 500,000,000 |  |  |  |  |  |  |  |  |  |
Reverse stock split ratio | 0.01 |  |  |  |  |  |  |  |  |  |
Subsequent Event [Member] | Maximum [Member] | Board of Directors [Member] |  |  |  |  |  |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |  |  |  |  |  |
Common stock, shares authorized (in shares) | 1,000,000,000 |  |  |  |  |  |  |  |  |  |
Reverse stock split ratio | 0.002 |  |  |  |  |  |  |  |  |  |
Subsequent Event [Member] | Registered Offering [Member] |  |  |  |  |  |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |  |  |  |  |  |
Number of registered common stock offering |  | 212,000,000 |  |  |  |  |  |  |  |  |
Number of pre-funded warrants |  | 38,000,000 |  |  |  |  |  |  |  |  |
Number of pre-funded warrants to purchase shares of common stock |  | 38,000,000 |  |  |  |  |  |  |  |  |
Gross proceeds from sale of warrants | $ |  | $ 5.0 |  |  |  |  |  |  |  |  |
Offering price | $ / shares |  | $ 0.02 |  |  |  |  |  |  |  |  |
Number of common stock purchase warrant |  | 1 |  |  |  |  |  |  |  |  |
Number of shares to purchase upon common stock purchase warrant |  | 2 |  |  |  |  |  |  |  |  |
Purchase of common stock warrants, pre-funded warrants shall be paid at offering, per unit | $ / shares |  | $ 0.019 |  |  |  |  |  |  |  |  |
Purchase of common stock warrants, pre-funded warrants shall be paid upon exercise, per unit | $ / shares |  | $ 0.001 |  |  |  |  |  |  |  |  |
Warrants expiration period |  | 5 years |  |  |  |  |  |  |  |  |
Warrants exercisable per share price (in dollars per share) | $ / shares |  | $ 0.02 |  |  |  |  |  |  |  |  |
Common stock, shares issued (in shares) |  | 434,981,824 |  |  |  |  |  |  |  |  |
Common stock, shares outstanding (in shares) |  | 434,981,824 |  |  |  |  |  |  |  |  |
Subsequent Event [Member] | Series D Warrants [Member] | Registered Offering [Member] |  |  |  |  |  |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |  |  |  |  |  |
Number of warrants to purchase aggregate shares of common stock |  | 500,000,000 |  |  |  |  |  |  |  |  |
Subsequent Event [Member] | Common Stock Issued [Member] | Registered Offering [Member] |  |  |  |  |  |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |  |  |  |  |  |
Offering share issued |  | 1 |  |  |  |  |  |  |  |  |
Subsequent Event [Member] | Warrants [Member] | Registered Offering [Member] |  |  |  |  |  |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |  |  |  |  |  |
Offering share issued |  | 1 |  |  |  |  |  |  |  |  |
Exchange Agreement [Member] | Subsequent Event [Member] |  |  |  |  |  |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |  |  |  |  |  |
Shares issuable upon warrants exercised |  |  |  |  |  | 108,900,000 |  |  |  |  |

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