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Description of Business - Additional Information (Details) - USD ($)
$ in Thousands
3 Months Ended 12 Months Ended
Dec. 31, 2017
Sep. 30, 2017
Jun. 30, 2017
Mar. 31, 2017
Dec. 31, 2016
Sep. 30, 2016
Jun. 30, 2016
Mar. 31, 2016
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Organization Consolidation And Presentation Of Financial Statements [Abstract]                      
Net loss $ 19,246 $ 12,596 $ 1,943 $ 11,332 $ 8,486 $ 1,004 $ 6,667 $ 1,813 $ 45,117 $ 17,971 $ 14,704
Net cash used in operating activities                 15,398 14,213 $ 16,420
Accumulated deficit $ 324,832       $ 279,188       $ 324,832 $ 279,188