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v3.19.2

Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2018 | Dec. 31, 2017
Cost of goods sold |  | $ (1,009) | $ (701)
Gross profit |  | 2,398 | 2,014
Operating expenses: |  |  |
Research and development expenses |  | 19,650 | 10,495
Selling, general and administrative expenses |  | 9,819 | 9,684
Total operating expenses |  | 29,469 | 20,179
Operating loss |  | (27,071) | (18,165)
Change in fair value of the warrant liability, net |  | 19,706 | 15,103
Gain on warrant extinguishment |  | 0 | 9,613
Loss on debt extinguishment |  | (1,123) | (29,924)
Loss on issuance of financial instrument |  | (2,826) | 0
Interest expense |  | (7,959) | (21,703)
Other income (expense) |  | 51 | (41)
Net loss |  | (19,222) | (45,117)
Other comprehensive loss: |  |  |
Foreign currency translation adjustments |  | 8 | 83
Comprehensive loss |  | $ (19,214) | $ (45,034)
Common share data: |  |  |
Basic and diluted loss per share | [1] | $ (0.72) | $ (3,250)
Weighted average number of basic and diluted shares outstanding | [1] | 26,705,375 | 14,039
Product Revenue [Member] |  |  |
Revenue |  | $ 3,378 | $ 2,715
Other Revenue [Member] |  |  |
Revenue |  | $ 29 |
[1] | reflects a one-for-three hundred and fifty (1:350) reverse stock split effected on November 6, 2017 and a one-for-five hundred (1:500) reverse stock split effected on May 2, 2018.

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