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Net Loss per Common Share - Summary of Reconciliation of Weighted Average Shares Outstanding Calculation (Details) - shares
3 Months Ended 6 Months Ended 12 Months Ended
Jun. 30, 2019
Jun. 30, 2019
Dec. 31, 2018
Dec. 31, 2017
[1]
Earnings Per Share [Abstract]        
Weighted average shares issued 17,910,886 18,676,912 2,738,944  
Weighted average pre-funded warrants 53,392,478 53,392,478 23,966,431  
Weighted average shares outstanding 71,303,364 72,069,390 26,705,375 [1] 14,039
[1] reflects a one-for-three hundred and fifty (1:350) reverse stock split effected on November 6, 2017 and a one-for-five hundred (1:500) reverse stock split effected on May 2, 2018.