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Summary of Significant Accounting Policies - Summary of Reconciliation of Weighted Average Shares Outstanding Calculation (Details) - shares | 12 Months Ended
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Dec. 31, 2018 | Dec. 31, 2017
Accounting Policies [Abstract] |  |  |
Weighted average shares issued |  | 3,913 |
Weighted average pre-funded warrants |  | 34,238 |
Weighted average shares outstanding | [1] | 38,151 | 21
[1] | reflects a one-for-three hundred and fifty (1:350) reverse stock split effected on November 6, 2017, a one-for-five hundred (1:500) reverse stock split effected on May 2, 2018, and a one-for-seven hundred (1:700) reverse stock split effected on December 24, 2019.

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- Definition Weighted average number of shares pre-funded warrants. + References No definition available. + Details
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- Definition Average number of shares or units issued and outstanding that are used in calculating basic and diluted earnings per share (EPS). + References No definition available. + Details
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