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Condensed Consolidated Statements of Stockholders' Equity (Deficit) (Unaudited) - USD ($)
$ in Thousands
Total
Common Stock [Member]
Preferred Stock [Member]
Additional Paid in Capital [Member]
Accumulated Deficit [Member]
Accumulated Other Comprehensive Income [Member]
Balance at Dec. 31, 2018 $ (14,939)     $ 329,065 $ (344,054) $ 50
Balance (in shares) at Dec. 31, 2018   14,715 101      
Increase (Decrease) in Stockholders' Equity [Roll Forward]            
Compensation expense for issuance of stock options 54     54    
Compensation expense for issuance of restricted stock 4     4    
Compensation expense for issuance of restricted stock (in shares)   20        
Issuance of Series D Preferred Stock 150     150    
Issuance of Series D Preferred Stock (in shares)     15      
Conversion of Series D Preferred Stock to Debt (1,160)     (1,160)    
Conversion of Series D Preferred Stock to Debt (in shares)     (116)      
Exercise of pre-funded warrants (in shares)   5,885        
Net loss (7,894)       (7,894)  
Total comprehensive income (loss) 7         7
Balance at Mar. 31, 2019 (23,778)     328,113 (351,948) 57
Balance (in shares) at Mar. 31, 2019   20,620        
Balance at Dec. 31, 2018 (14,939)     329,065 (344,054) 50
Balance (in shares) at Dec. 31, 2018   14,715 101      
Increase (Decrease) in Stockholders' Equity [Roll Forward]            
Net loss (21,371)          
Balance at Sep. 30, 2019 (18,825)     364,750 (383,664) 89
Balance (in shares) at Sep. 30, 2019   26,110 42,082      
Balance at Mar. 31, 2019 (23,778)     328,113 (351,948) 57
Balance (in shares) at Mar. 31, 2019   20,620        
Increase (Decrease) in Stockholders' Equity [Roll Forward]            
Compensation expense for issuance of stock options 75     75    
Exercise of pre-funded warrants (in shares)   5,399        
Exercise of warrants into common stock 13     13    
Exercise of warrants into common stock (in shares)   91        
Net loss (5,959)       (5,959)  
Total comprehensive income (loss) (80)         (80)
Balance at Jun. 30, 2019 (29,729)     328,201 (357,907) (23)
Balance (in shares) at Jun. 30, 2019   26,110        
Increase (Decrease) in Stockholders' Equity [Roll Forward]            
Compensation expense for issuance of stock options 70     70    
Issuance of Series E Preferred Stock 29,575     42,915 (13,340)  
Issuance Of Series E Preferred Stock, Shares     32,572      
Issuance of Series E-1 Preferred Stock 9,510     14,408 (4,898)  
Issuance Of Series E1 Preferred Stock, Shares     9,510      
Fair value of warrants issued (20,844)     (20,844)    
Net loss (7,519)       (7,519)  
Total comprehensive income (loss) 112         112
Balance at Sep. 30, 2019 (18,825)     364,750 (383,664) 89
Balance (in shares) at Sep. 30, 2019   26,110 42,082      
Balance at Dec. 31, 2019 (6,357) $ 1   364,785 (371,171) 28
Balance (in shares) at Dec. 31, 2019   67,091 41,517      
Increase (Decrease) in Stockholders' Equity [Roll Forward]            
Compensation expense for issuance of stock options 25     25    
Compensation expense for issuance of restricted stock 30     30    
Compensation expense for issuance of restricted stock (in shares)   2,717        
Conversion of Preferred stock into common stock (in shares)   2,915 (70)      
Fractional rounding related to reverse stock split (in shares)   50        
Registration of Series E and Series E-1 Preferred stock and related warrants (106)     (106)    
Fair value of warrants reclassified from liability to equity 6,199     6,199    
Net loss (7,861)       (7,861)  
Total comprehensive income (loss) 65         65
Balance at Mar. 31, 2020 (8,005) $ 1   370,933 (379,032) 93
Balance (in shares) at Mar. 31, 2020   72,773 41,447      
Balance at Dec. 31, 2019 $ (6,357) $ 1   364,785 (371,171) 28
Balance (in shares) at Dec. 31, 2019   67,091 41,517      
Increase (Decrease) in Stockholders' Equity [Roll Forward]            
Conversion of Preferred stock into common stock (in shares) 2,000,224          
Exercise of pre-funded warrants (in shares) 6,000          
Net loss $ (17,127)          
Balance at Sep. 30, 2020 3,276 $ 40   391,545 (388,298) (11)
Balance (in shares) at Sep. 30, 2020   4,035,558 21,473      
Balance at Mar. 31, 2020 (8,005) $ 1   370,933 (379,032) 93
Balance (in shares) at Mar. 31, 2020   72,773 41,447      
Increase (Decrease) in Stockholders' Equity [Roll Forward]            
Compensation expense for issuance of restricted stock 606 $ 1   605    
Compensation expense for issuance of restricted stock (in shares)   70,259        
Conversion of Preferred stock into common stock (1) $ 15   (16)    
Conversion of Preferred stock into common stock (in shares)   1,549,609 (15,497)      
Exercise of pre-funded warrants (in shares)   6,000        
Public Offering - issuance of common stock and warrants 19,378 $ 18   19,360    
Public Offering - issuance of common stock and warrants (in shares)   1,823,000        
Net loss (4,275)       (4,275)  
Total comprehensive income (loss) (1)         (1)
Balance at Jun. 30, 2020 7,702 $ 35   390,882 (383,307) 92
Balance (in shares) at Jun. 30, 2020   3,521,641 25,950      
Increase (Decrease) in Stockholders' Equity [Roll Forward]            
Conversion of Preferred stock into common stock   $ 4   (4)    
Conversion of Preferred stock into common stock (in shares)   447,700 (4,477)      
Exercise of warrants into common stock 602 $ 1   601    
Exercise of warrants into common stock (in shares)   60,117        
ATM Offering 66     66    
ATM Offering, Shares   6,100        
Net loss (4,991)       (4,991)  
Total comprehensive income (loss) (103)         (103)
Balance at Sep. 30, 2020 $ 3,276 $ 40   $ 391,545 $ (388,298) $ (11)
Balance (in shares) at Sep. 30, 2020   4,035,558 21,473