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Income Taxes - Income tax reconciliation (Details) - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2018 | Dec. 31, 2017
Provision for income taxes [Abstract] |  |
Income taxes using U.S federal statutory rate | $ (4,037) | $ (15,340)
Tax Cuts and Jobs Act |  | 143
Nondeductible interest | 2,273 | 6,912
Loss on extinguishment of debt | 236 | 10,174
Loss of tax benefit of federal net operating loss carryforwards | (588) | 5,067
Loss of tax benefit of state net operating loss carryforwards | 1,040 | 1,373
Loss of tax benefit of federal tax credit carryforwards | 495 | 324
Amortization of gain on IP migration |  | 767
State income taxes, net of federal benefit | (2,355) | (1,339)
Foreign rate differential | 1,166 | 1,196
Valuation allowance | 6,323 | (1,423)
Derivative charge | (4,138) | (8,403)
Stock option exercises and cancellations | 215 | 841
Research and development costs | (636) | (295)
Other | $ 6 | $ 3

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