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Stockholders' Equity - Common Stock Issuances - Additional Information (Details) - USD ($) |  | 1 Months Ended | 12 Months Ended
--- | --- | --- | ---
May 05, 2020 | Apr. 30, 2019 | Dec. 31, 2020 | Dec. 31, 2019
Stockholders Equity Note [Line Items] |  |  |  |  |  |  |
Warrant exercise price |  |  |  | $ 10.00 |  |  |
Debt instrument, conversion price |  | $ 10.00 |  |  |  |  |
Compensation expense for issuance of restricted stock (in shares) |  |  |  | 72,976 |  | 20 |
Common stock grant date fair value |  |  |  | $ 636,000 |  | $ 4,000 |
Gross proceeds from issuance of common stock |  |  |  | $ 230,000 |  |  |
Exercise of pre-funded Series D Warrants (in shares) |  |  |  | 6,000 |  | 11,285 |
Stock issued during period shares associated other warrants |  |  |  | 185,803 |  |  |
Proceeds from exercise of warrants |  |  |  | $ 1,858,000 |  | $ 0 |
Common stock, shares issued (in shares) |  |  | 92 | 5,996,101 | [1] | 67,091 | [1]
Purchase of warrants |  |  | 82,521 |  |  |  |
Weighted average exercise price |  |  | $ 170 |  |  |  |
Loss in exchange of common stock with warrants |  |  | $ 6,000 |  |  |  |
Series F warrants [Member] |  |  |  |  |  |  |
Stockholders Equity Note [Line Items] |  |  |  |  |  |  |
Warrants issued to purchase of common stock |  | 2,224,900 |  |  |  |  |
Warrant exercise price |  | $ 10.00 |  |  |  |  |
Pre-Funded Warrants [Member] |  |  |  |  |  |  |
Stockholders Equity Note [Line Items] |  |  |  |  |  |  |
Warrants issued to purchase of common stock |  | 377,000 |  |  |  |  |
IPO [Member] |  |  |  |  |  |  |
Stockholders Equity Note [Line Items] |  |  |  |  |  |  |
Proceeds on Public Offering (1) | [2] |  |  | $ 19,378,000 |  | $ 0 |
Common Stock [Member] |  |  |  |  |  |  |
Stockholders Equity Note [Line Items] |  |  |  |  |  |  |
Proceeds on Public Offering (1) |  | $ 21,996,000 |  |  |  |  |
Underwriting discounts and other offering expenses |  | $ 2,618,000 |  |  |  |  |
Compensation expense for issuance of restricted stock (in shares) |  |  |  |  |  | 20 |
Common Stock [Member] | IPO [Member] |  |  |  |  |  |  |
Stockholders Equity Note [Line Items] |  |  |  |  |  |  |
Shares issued in public offering |  | 1,823,000 |  |  |  |  |
2019 Warrants [Member] |  |  |  |  |  |  |
Stockholders Equity Note [Line Items] |  |  |  |  |  |  |
Warrant exercise price |  | $ 10.00 |  | $ 10.00 |  |  |
[1] | reflects, a one-for-seven hundred (1:700) reverse stock split effected on December 24, 2019.
[2] | May 2020 Public Offering gross proceed were $21,996, with issuance costs of $2,618

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