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Stockholders' Equity - Preferred Stock Issuances - Additional Information (Details) - USD ($)
12 Months Ended
Nov. 07, 2019
Aug. 19, 2019
Jul. 11, 2019
Mar. 29, 2019
Nov. 06, 2018
Dec. 31, 2020
Dec. 31, 2019
Nov. 23, 2020
Sep. 30, 2020
May 05, 2020
Jun. 06, 2019
Nov. 05, 2018
Stockholders Equity Note [Line Items]                        
Preferred stock, shares authorized (in shares)           10,000,000 10,000,000          
Preferred stock, par value (in dollars per share)           $ 0.01 $ 0.01          
Common stock, par value (in dollars per share)           $ 0.01 [1] $ 0.01 [1] $ 0.01        
Common stock, shares authorized (in shares)           40,000,000 [1] 40,000,000 [1] 40,000,000 1,000,000,000      
Number of preferred stock and warrants issued upon conversion           2,084,507 13,455          
Fair value of warrants issued           $ 0 $ 20,844,000          
Debt instrument, conversion price                   $ 10.00    
Warrant exercise price           $ 10.00            
Preferred stock, shares outstanding (in shares)           20,631 41,517          
Preferred stock, aggregate stated value           $ 0 $ 0          
2019 Warrants [Member]                        
Stockholders Equity Note [Line Items]                        
Warrant exercise price           $ 10.00       $ 10.00    
Number of shares called upon exercise of warrant 824,587                      
Deemed dividend for triggering of warrant down round feature           $ 55,000            
Estimated fair value of warrant reclassified from Derivative liability to equity           $ 6,200,000            
Common Stock [Member]                        
Stockholders Equity Note [Line Items]                        
Conversion of stock, shares issued 813,473                      
August 2019 Private Placement [Member] | 2019 Warrants [Member]                        
Stockholders Equity Note [Line Items]                        
Fair value of warrants issued   $ 20,844,000                    
Series A Preferred Stock [Member]                        
Stockholders Equity Note [Line Items]                        
Preferred stock, shares authorized (in shares)           4,200            
Series C Preferred Stock [Member]                        
Stockholders Equity Note [Line Items]                        
Preferred stock, shares authorized (in shares)           2,360            
Series C Preferred Stock [Member]                        
Stockholders Equity Note [Line Items]                        
Preferred stock, shares authorized (in shares)           590            
Series E Preferred Stock [Member]                        
Stockholders Equity Note [Line Items]                        
Preferred stock, shares authorized (in shares)           40,000            
Debt instrument, conversion price                     $ 1,500  
Series E1 Preferred Stock [Member]                        
Stockholders Equity Note [Line Items]                        
Preferred stock, shares authorized (in shares)           12,960            
Series E Convertible Preferred Stock [Member]                        
Stockholders Equity Note [Line Items]                        
Conversion of stock preferred shares converted           20,887 565          
Series E Convertible Preferred Stock [Member] | July Two Thousand Nineteen Private Placement                        
Stockholders Equity Note [Line Items]                        
Preferred stock, par value (in dollars per share)     $ 0.01                  
Number of shares issued     32,572                  
Series E Convertible Preferred Stock [Member] | July Two Thousand Nineteen Private Placement | Securities Purchase Agreement                        
Stockholders Equity Note [Line Items]                        
Number of shares issued     20,000                  
Shares issued, price per share     $ 1,000                  
Series E Preferred Stock and Related Warrants [Member] | July Two Thousand Nineteen Private Placement                        
Stockholders Equity Note [Line Items]                        
Debt and warrants exchanged for preferred stock     $ 11,800,000                  
Number of preferred stock and warrants issued upon conversion     11,500                  
Value of accounts payable exchanged     $ 100,000                  
Number of shares issued upon exchange of accounts payable     149                  
Number of shares issued upon exchange of investor waiver rights     923                  
Series E-1 Convertible Preferred Stock [Member]                        
Stockholders Equity Note [Line Items]                        
Conversion of stock preferred shares converted           20,887 565          
Series E-1 Convertible Preferred Stock [Member] | August 2019 Private Placement [Member] | Securities Purchase Agreement                        
Stockholders Equity Note [Line Items]                        
Preferred stock, par value (in dollars per share)   $ 0.01                    
Number of shares issued   9,510                    
Shares issued, price per share   $ 1,000                    
Convertible Preferred Stock                        
Stockholders Equity Note [Line Items]                        
Debt instrument, conversion price $ 23.04         $ 42.00            
Warrant exercise price 23.04         $ 42.00            
Warrant exercisable term           5 years            
Registration cost of shares of common stock           $ 106,000            
Excess of the fair value of the common stock           $ 12,000,000            
Convertible Preferred Stock | 2019 Warrants [Member]                        
Stockholders Equity Note [Line Items]                        
Debt instrument, conversion price           $ 10.00            
Convertible Preferred Stock | August 2019 Private Placement [Member]                        
Stockholders Equity Note [Line Items]                        
Net proceeds from issuance of preferred stock   $ 26,500,000                    
Beneficial conversion feature   $ 18,238,000                    
Preferred Stock and 2019 Warrants [Member]                        
Stockholders Equity Note [Line Items]                        
Conversion of stock, description           the Conversion Price of the Preferred Stock and the Exercise Price of the 2019 Warrants were initially subject to adjustment in each of the following circumstances: (i) on the third trading day following the date that the Company effects a reverse stock split, or the Reverse Split Reset Date, (ii) the date that the initial registration statement covering the shares of common stock issuable upon the conversion of the Preferred Stock and the exercise of the 2019 Warrants is declared effective by the SEC, or the Registration Reset Date, and (iii) in the event that all of the shares of common stock which we were required to register with the SEC were not then registered on an effective registration statement, the date that all of the shares underlying the respective Preferred Stock and 2019 Warrants may be sold pursuant to Rule 144, or the Rule 144 Reset Date, each of such reset dates, a Reset Date and, collectively, the Reset Dates. On each Reset Date, the Conversion Price and the Exercise Price were to be reduced, and only reduced, to equal the lesser of (x) the then effective Conversion Price or Exercise Price, as applicable, and (y) 90% of the average of the five daily volume weighted average prices of the common stock immediately prior to each Reset Date, or the Reset Formula.            
Private Placements and Debt Exchange [Member]                        
Stockholders Equity Note [Line Items]                        
Conversion price and exercise price per share $ 16.10                      
Private Placements and Debt Exchange [Member] | Common Stock [Member]                        
Stockholders Equity Note [Line Items]                        
Shares issued in public offering 3,429,680                      
Series D Preferred Shares [Member]                        
Stockholders Equity Note [Line Items]                        
Preferred stock, shares authorized (in shares)           10,000            
Preferred stock, par value (in dollars per share)                       $ 0.01
Number of shares issued         101   15          
Net proceeds from the sale of Series E and E-1 Preferred Stock and warrants         $ 150,000 $ 0 $ 150,000          
Preferred stock shares exchanged       116                
Preferred stock, aggregate stated value       $ 1,160,000                
Proceeds from exchange of senior secured promissory note       400,000                
Issuance of senior secured promissory note in exchange of preferred stock       $ 1,560,000                
Interest rate       8.00%                
Debt instrument maturity date       Apr. 01, 2020                
[1] reflects, a one-for-seven hundred (1:700) reverse stock split effected on December 24, 2019.