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Stockholders' Equity - Common Stock Issuances - Additional Information (Details) - USD ($)
 1 Months Ended 12 Months Ended
May 05, 2020
Apr. 30, 2019
Dec. 31, 2020
Dec. 31, 2019
Stockholders Equity Note [Line Items]        
Warrant exercise price     $ 10.00  
Debt instrument, conversion price $ 10.00      
Compensation expense for issuance of restricted stock (in shares)     72,976 20
Common stock grant date fair value     $ 636,000 $ 4,000
Gross proceeds from issuance of common stock     $ 230,000  
Exercise of pre-funded Series D Warrants (in shares)     6,000 11,285
Stock issued during period shares associated other warrants     185,803  
Proceeds from exercise of warrants     $ 1,858,000 $ 0
Common stock, shares issued (in shares)   92 5,996,101 [1] 67,091 [1]
Purchase of warrants   82,521    
Weighted average exercise price   $ 170    
Loss in exchange of common stock with warrants   $ 6,000    
Series F warrants [Member]        
Stockholders Equity Note [Line Items]        
Warrants issued to purchase of common stock 2,224,900      
Warrant exercise price $ 10.00      
Pre-Funded Warrants [Member]        
Stockholders Equity Note [Line Items]        
Warrants issued to purchase of common stock 377,000      
IPO [Member]        
Stockholders Equity Note [Line Items]        
Proceeds on Public Offering (1) [2]     $ 19,378,000 $ 0
Common Stock [Member]        
Stockholders Equity Note [Line Items]        
Proceeds on Public Offering (1) $ 21,996,000      
Underwriting discounts and other offering expenses $ 2,618,000      
Compensation expense for issuance of restricted stock (in shares)       20
Common Stock [Member] | IPO [Member]        
Stockholders Equity Note [Line Items]        
Shares issued in public offering 1,823,000      
2019 Warrants [Member]        
Stockholders Equity Note [Line Items]        
Warrant exercise price $ 10.00   $ 10.00  
[1] reflects, a one-for-seven hundred (1:700) reverse stock split effected on December 24, 2019.
[2] May 2020 Public Offering gross proceed were $21,996, with issuance costs of $2,618