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Stockholders' Equity (Tables)
12 Months Ended
Aug. 06, 2021
Dec. 31, 2021
Stockholders' Equity Note [Abstract]    
Summary of Avenue Warrant Valued Using the Black-Scholes Option Pricing Method
date market price of the Company’s common stock. Interest expense incurred was $675 for the year ended December 31, 2021
.
The
 
Avenue Warrant was valued at issuance at $1,309 using the Black-Scholes option pricing method using the following assumptions:
 
    
August 6,
2021
 
Contractual term (years)
     5.07  
Expected volatility
     187.0
Risk-free interest rate
     0.77
Expected dividends
     0.00
The Company values stock options using the Black-Scholes option pricing model and used the following assumptions during the reporting periods:
 
    
Years ended December 31,
    
2021
  
2020
Expected terms (years)
  
5.13 - 6.27
   5.77
Expected volatility
  
177.52% - 181.33%
   181.00%
Risk-free interest rate
  
0.74% - 1.31%
  
0.27% - 0.40%
Expected dividends
   0.00%    0.00%
Summary of Stock Option Activity  
The following is a summary of stock option activity for the year ended December 31, 2021:
 
   
Number of Options
   
Weighted Average
Exercise Price Per Share
   
Weighted Average
Remaining
Contractual Term
(in years)
   
Aggregate Intrinsic
Value
 
Outstanding at January 1, 2021
    1,078,499     $ 12.68                  
Granted
    671,750       10.07                  
Exercised
    (439     9.85                  
Expired
    (392     11.67                  
Cancelled/Forfeited
    (16,958     10.59                  
   
 
 
   
 
 
   
 
 
   
 
 
 
Outstanding at December 31, 2021
    1,732,460     $ 11.69       9.1     $ —    
   
 
 
   
 
 
   
 
 
   
 
 
 
Exercisable at December 31, 2021
    600,113     $ 12.08       9.0     $ —    
   
 
 
   
 
 
   
 
 
   
 
 
 
Summary of Stock Option Shares Outstanding and Exercisable  
The following table summarizes information for stock option shares outstanding and exercisable at December 31, 2021:
 
           
Options Exercisable
 
Range of Exercise Prices
  
Outstanding Number
of Options
    
Weighted Average
Remaining Option Term
(in years)
    
Number of Options
 
$9.58 - $10.99
     631,211        9.6        153,733  
$11.00 - $14.99
     968,750        8.8        393,481  
$15.00 - $24.99
     132,000        8.8        52,400  
    
 
 
    
 
 
    
 
 
 
$25 +
     499        7.1        499  
    
 
 
    
 
 
    
 
 
 
       1,732,460        9.0        600,113  
    
 
 
    
 
 
    
 
 
 
Summary of Recognized Share-based Compensation Cost  
At December 31, 2021, there was approximately $7,406 of aggregate unrecognized compensation expense related to employee and board stock option grants. The cost is expected to be recognized over a weighted average period of 2.01 years. For the years ended December 31, 2021 and 2020, the Company recognized compensation expense $7,832 and $3,505, respectively, related to stock options granted to employees and board members, which were charged to the statement of operations as detailed below:
 
    
Years ended
December 31,
 
    
2021
    
2020
 
Selling, general and administrative
   $ 5,334      $ 2,304  
Research and development
     2,311        1,110  
Cost of goods sold
     187        91  
    
 
 
    
 
 
 
Total
   $ 7,832      $ 3,505  
    
 
 
    
 
 
 
Subsequent to December 31, 2021, the Company made aggregate ten-year option grants to purchase 545,083 shares of common stock with exercise prices ranging from $6.61 to $7.25 per share. Vesting occurs over a three-year period.
Summary of Warrant Activity  
The following is a summary of warrant activity for the year ended December 31, 2021:
 
    
Warrants
    
Weighted Average
Exercise Price
    
Weighted Average
Remaining Life
(Years)
 
Outstanding at January 1, 2021
     4,236,687      $ 9.13           
Warrants issued
     127,755        0.01           
Warrants exercised
     (469,933      5.88           
Warrants expired
     (11      10.00           
    
 
 
    
 
 
    
 
 
 
Outstanding at December 31, 2021
     3,894,498      $ 9.27        3.2  
    
 
 
    
 
 
    
 
 
 
Exercisable at December 31, 2021
     3,894,498      $ 9.27        3.2  
    
 
 
    
 
 
    
 
 
 
Schedule of Information Related to Stock Warrants Outstanding and Exercisable  
The following table presents information related to stock warrants at December 31, 2021:
 
           
Warrants Exercisable
 
Range of Exercise Prices
  
Outstanding Number
of Warrants
    
Weighted Average
Remaining Warrants
Term (in years)
    
Number of
Warrants
 
$0.01
     283,755        3.9        283,755  
$10.00
     3,610,743        3.2        3,610,743  
    
 
 
    
 
 
    
 
 
 
       3,894,498        3.2        3,894,498