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Commitments and contingencies - Additional Information (Details) $ in Thousands, € in Millions				12 Months Ended
	Mar. 31, 2021	Jul. 27, 2020 USD ($)	Apr. 01, 2020	Dec. 31, 2021 USD ($)	Apr. 01, 2021 USD ($)	Apr. 01, 2021 EUR (€)	Dec. 31, 2020 USD ($)
Loss Contingencies [Line Items]
Percentage of enrolled patients	87.00%
Increase in revenue recognition				$ 1,742
Medac [Member]
Loss Contingencies [Line Items]
Due from related parties					$ 1,160	€ 1,000
Agreement date			Dec. 10, 2018
Pending Litigation [Member]
Loss Contingencies [Line Items]
Unpaid compensation amounts claimed		$ 1,140
Accrued unpaid compensation amounts							$ 1,140

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