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Net Loss per Common Share | 3 Months Ended
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Mar. 31, 2022
Earnings Per Share [Abstract] |
Net Loss per Common Share |
(10) | Net Loss per Common Share
Basic net loss per share is determined by dividing net loss by the weighted average shares of common stock outstanding during the period, without consideration of potentially dilutive securities, except for those shares that are issuable for little or no cash consideration. Diluted net loss per share is determined by dividing net loss by diluted weighted average shares outstanding. Diluted weighted average shares reflects the dilutive effect, if any, of potentially dilutive common shares, such as stock options and warrants calculated using the treasury stock method. In periods with reported net operating losses, all common stock options and warrants are generally deemed anti-dilutive such that basic net loss per share and diluted net loss per share are equal. The following potentially dilutive securities were excluded from the computation of earnings per share as of March 31, 2022 and 2021 because their effects would be anti-dilutive:
|  | March 31, |
|  | 2022 |  |  | 2021 |
Stock options |  |  | 2,238,103 |  |  |  | 1,078,499 |
Common stock warrants - equity |  |  | 3,894,498 |  |  |  | 3,994,107 |
Assumed conversion of Series E and Series E-1 Preferred Stock |  |  | 1,135,721 |  |  |  | 2,048,101 |
Assumed conversion of convertible notes |  |  | 488,031 |  |  |  | 146,288 |
Total |  |  | 7,756,353 |  |  |  | 7,266,995 |
At March 31, 2022, the Company had 283,755 pre-funded warrants outstanding. The following table provides a reconciliation of the weighted average shares outstanding calculation for the three months ended March 31, 2022 and 2021:
|  | Three months ended March 31, |
|  | 2022 |  |  | 2021 |
Weighted average shares issued |  |  | 7,906,728 |  |  |  | 6,125,922 |
Weighted average pre-funded warrants |  |  | 283,755 |  |  |  | 371,000 |
Weighted average shares outstanding |  |  | 8,190,483 |  |  |  | 6,496,922 |

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- Definition The entire disclosure for earnings per share. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 50 -Paragraph 3 -URI http://asc.fasb.org/extlink&oid=109243012&loc=SL65017193-207537 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=124432515&loc=d3e3550-109257 Reference 3: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 260 -URI http://asc.fasb.org/topic&trid=2144383 Reference 4: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 50 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=124432515&loc=d3e3630-109257 + Details
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