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Stockholders' Equity (Deficit) (Tables)
6 Months Ended
Aug. 06, 2021
Jun. 30, 2022
Stockholders' Equity Note [Abstract]    
Summary of Avenue Warrant Valued Using the Black-Scholes Option Pricing Method
The Avenue Warrant was valued at issuance at $1.3 million using the Black-Scholes option pricing method using the following assumptions:
 
    
August 6,

2021
 
Contractual term (years)
     5.07  
Expected volatility
     187.0
Risk-free interest rate
     0.77
Expected dividends
     0.00
The Company values stock options using the Black-Scholes option pricing model and used the following assumptions during the reporting periods:
 
    
Six months ended June 30,
    
2022
  
2021
Expected terms (years)
  
5.23 - 6.46
  
5.86
Expected volatility
  
174.81% -180.33%
  
 178.33 
Risk-free interest rate
  
1.75% -2.93%
  
0.9%
Expected dividends
   0.00%   
0.00%
Summary of Stock Option Activity  
The following is a summary of stock option activity for the six months ended June 30, 2022:
 
    
Number of Options
    
Weighted Average
Exercise Price Per Share
    
Weighted Average
Remaining
Contractual Term
(in years)
    
Aggregate Intrinsic
Value
 
Outstanding at January 1, 2022
     1,732,460      $ 11.69                    
Granted
     650,083        7.05                    
Expired
     (29,116      10.73                    
Cancelled/Forfeited
     (42,034      10.35                    
    
 
 
    
 
 
    
 
 
    
 
 
 
Outstanding at June 30, 2022
     2,311,393      $ 10.42        8.7      $ —    
    
 
 
    
 
 
    
 
 
    
 
 
 
Exercisable at June, 2022
     952,670      $ 11.48        8.4      $ —    
    
 
 
    
 
 
    
 
 
    
 
 
 
Summary of Stock Option Shares Outstanding and Exercisable  
The following table summarizes information for stock option shares outstanding and exercisable at June 
3
0, 2022:
 
           
Options Exercisable
 
Range of Exercise Prices
  
Outstanding Number of
Options
    
Weighted Average
Remaining Option Term
(in years)
    
Number of Options
 
$6.24 - $53.85
     2,310,894        8.7        952,171  
$53.85+
     499        6.6        499  
    
 
 
    
 
 
    
 
 
 
       2,311,393        8.4        952,670  
    
 
 
    
 
 
    
 
 
 
Summary of Recognized Share-based Compensation Cost  
The following is a summary of share-based compensation expense in the statement of operations for the three and six months ended June 30, 2022 and
2021 (in thousands):
 
    
Three months ended
 
J
u
ne 30
,
    
Six months ended June 30,
 
    
2022
    
2021
    
2022
    
2021
 
Selling, general and administrative
   $ 918      $ 1,124      $ 1,958      $ 2,590  
Research and development
     503        463        1,025        1,093  
Cost of goods sold
     52        39        108        91  
    
 
 
    
 
 
    
 
 
    
 
 
 
Total
   $ 1,473      $ 1,626      $ 3,091      $ 3,774  
    
 
 
    
 
 
    
 
 
    
 
 
 
Summary of Warrant Activity  
The following is a summary of warrant activity for the six months ended June 30, 2022:
 
    
Warrants
    
Weighted Average

Exercise Price
    
Weighted Average

Remaining Life

(in years)
 
Outstanding at January 1, 2022
     3,894,498      $ 9.27           
Warrants issued
     —          —             
Warrants exercised
     —          —             
Warrants expired
     —          —             
    
 
 
    
 
 
    
 
 
 
Outstanding at June 30, 2022
     3,894,498      $ 9.27        2.7  
    
 
 
    
 
 
    
 
 
 
Exercisable at June 30, 2022
     3,894,498      $ 9.27        2.7  
    
 
 
    
 
 
    
 
 
 
Schedule of Information Related to Stock Warrants Outstanding and Exercisable  
The following table presents information related to stock warrants at June 30, 2022
 
           
Warrants Exercisable
 
Range of Exercise Prices
  
Outstanding Number

of Warrants
    
Weighted Average

Remaining Warrant Term

(in years)
    
Number of Warrants
 
$0.01
     283,755        3.4        283,755  
$10.00
     3,610,743        2.7        3,610,743  
    
 
 
    
 
 
    
 
 
 
       3,894,498        2.7        3,894,498