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Commitments and contingencies - Additional Information (Details) € in Millions	Jun. 30, 2022 USD ($)	Apr. 01, 2020	Mar. 31, 2022 USD ($)	Dec. 31, 2021 USD ($)	Apr. 01, 2021 USD ($)	Apr. 01, 2021 EUR (€)
Loss Contingencies [Line Items]
Percentage of enrolled patients	87.00%
Inventory	$ 2,040,000			$ 1,412,000
Medac [Member]
Loss Contingencies [Line Items]
Due from related parties					$ 1,000	€ 1
Agreement date		Dec. 10, 2018
Inventory			$ 200,000

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