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v3.22.2.2

Commitments and contingencies - Additional Information (Details) $ in Thousands, € in Millions | Oct. 25, 2022 | Sep. 30, 2022 USD ($) | Apr. 01, 2020 | Mar. 31, 2022 USD ($) | Dec. 31, 2021 USD ($) | Apr. 01, 2021 USD ($) | Apr. 01, 2021 EUR (€)
--- | --- | --- | --- | --- | --- | --- | ---
Loss Contingencies [Line Items] |  |  |  |  |  |  |
Percentage of enrolled patients |  | 87.00% |  |  |  |  |
Inventory |  | $ 1,926 |  |  | $ 1,412 |  |
Medac [Member] |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |
Due from related parties |  |  |  |  |  | $ 1,000 | € 1
Agreement date |  |  | Dec. 10, 2018 |  |  |  |
Inventory |  |  |  | $ 200 |  |  |
Medac [Member] | Definitive Settlement Agreement [Member] | Other Noncurrent Liabilities [Member] |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |
Accrued unpaid compensation amounts |  | $ 1,200 |  |  |  |  |
Medac [Member] | Subsequent Event [Member] | Definitive Settlement Agreement [Member] |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |
Term over which the royalty is to be paid | 5 years |  |  |  |  |  |

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