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Stockholders' Equity (Deficit) (Tables)
9 Months Ended
Aug. 06, 2021
Sep. 30, 2022
Stockholders' Equity Note [Abstract]    
Summary of Avenue Warrant Valued Using the Black-Scholes Option Pricing Method
The Avenue Warrant was valued at issuance at $1.3 million using the Black-Scholes option pricing method using the following assumptions:
 
    
August 6,
2021
 
Contractual term (years)
     5.07  
Expected volatility
     187.0
Risk-free interest rate
     0.77
Expected dividends
     0.00
The Company values stock options using the Black-Scholes option pricing model and used the following assumptions:
 
    
Nine months ended September 30,
    
2022
  
2021
Expected terms (years)
  
0.7 - 8.4
  
5.1 - 6.3
Expected volatility
  
166.4% - 180.3%
  
178.3% - 181.3%
Risk-free interest rate
  
1.8% - 2.9%
   0.7% - 1.1%
Expected dividends
   0.00%    0.00%
Summary of Stock Option Activity  
The following is a summary of stock option activity for the nine months ended September 30, 2022:
 
    
Number of
Options
    
Weighted Average
Exercise Price
Per Share
    
Weighted Average
Remaining
Contractual
Term (in years)
    
Aggregate
Intrinsic
Value
 
Outstanding at January 1, 2022
     1,732,460      $ 11.69                    
Granted
     650,083        7.05                    
Expired
     (36,628      10.44                    
Cancelled/Forfeited
     (95,960      9.69                    
    
 
 
    
 
 
    
 
 
    
 
 
 
Outstanding at September 30, 2022
     2,249,955      $ 10.46        8.4      $ —    
    
 
 
    
 
 
    
 
 
    
 
 
 
Exercisable at September 30, 2022
     1,143,154      $ 11.27        8.1      $ —    
    
 
 
    
 
 
    
 
 
    
 
 
 
Summary of Stock Option Shares Outstanding and Exercisable  
The following table summarizes information for stock option shares outstanding and exercisable at September 30, 2022:
 
           
Options Exercisable
 
Range of Exercise Prices
  
Outstanding
Number of
Options
    
Weighted Average
Remaining Option
Term (in years)
    
Number of
Options
 
$6.24 - $53.85
     2,249,456        8.4        1,142,655  
$53.85+
     499        6.3        499  
    
 
 
    
 
 
    
 
 
 
       2,249,955        8.1        1,143,154  
    
 
 
    
 
 
    
 
 
 
Summary of Recognized Share-based Compensation Cost  
The following is a summary of share-based compensation expense in the statement of operations for the three and nine months ended September 30, 2022 and 2021 (in thousands):
 
    
Three months
ended September 30
    
Nine months ended
September 30,
 
    
2022
    
2021
    
2022
    
2021
 
Selling, general and administrative
   $ 857      $ 1,655      $ 2,816      $ 4,245  
Research and development
     346        734        1,370        1,827  
Cost of goods sold
     52        60        160        152  
    
 
 
    
 
 
    
 
 
    
 
 
 
Total
   $ 1,255      $ 2,449      $ 4,346      $ 6,224  
    
 
 
    
 
 
    
 
 
    
 
 
 
Summary of Warrant Activity  
The following is a summary of warrant activity for the nine months ended September 30, 2022:
 
    
Warrants
    
Weighted Average
Exercise Price
    
Weighted Average
Remaining Life
(in years)
 
Outstanding at January 1, 2022
     3,894,498      $ 9.27           
Warrants issued
     566,751        .01           
Warrants exercised
     —          —             
Warrants expired
     —          —             
    
 
 
    
 
 
    
 
 
 
Outstanding at September 30, 2022
     4,461,249      $ 8.09        2.8  
    
 
 
    
 
 
    
 
 
 
Exercisable at September 30, 2022
     4,461,249      $ 8.09        2.8  
    
 
 
    
 
 
    
 
 
 
Schedule of Information Related to Stock Warrants Outstanding and Exercisable  
The following table presents information related to stock warrants at September 30, 2022:
 
           
Warrants Exercisable
 
Range of Exercise Prices
  
Outstanding Number
of Warrants
    
Weighted Average
Remaining
Warrant Term
    
Number of
Warrants
 
$0.01
     850,506        4.3        850,506  
$10.00
     3,610,743        2.4        3,610,743  
    
 
 
    
 
 
    
 
 
 
       4,461,249        2.8        4,461,249