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Consolidated Statements of Stockholders' Equity (Deficit) - USD ($)
$ in Thousands
Total
Common Stock [Member]
Preferred Stock [Member]
Additional Paid in Capital [Member]
Accumulated Deficit [Member]
Accumulated Other Comprehensive Income (Loss) [Member]
Balance at Dec. 31, 2020 $ 22,078 $ 60 $ 0 $ 417,449 $ (395,327) $ (104)
Balance (in shares) at Dec. 31, 2020   5,996,101 20,631      
Increase (Decrease) in Stockholders' Equity [Roll Forward]            
Compensation expense for issuance of stock options 7,832     7,832    
Shares settled for services 57     57    
Shares settled for services (in shares)   2,636        
Conversion of preferred stock into common stock   $ 9   (9)    
Conversion of Preferred stock into common stock (in shares)   927,379 (9,274)      
Exercise of warrants into common stock 2,458 $ 5   2,453    
Exercise of warrants into common stock (in shares)   465,173        
Proceeds allocated to warrant 1,171     1,171    
Cash issuance costs of warrant (44)     (44)    
Exercise of options into common stock 4     4    
Exercise of options into common stock (shares)   439        
Common stock issued in connection with ATM Offering 3,923 $ 5   3,918    
Common stock issued in connection with ATM Offering (Shares)   515,000        
Net loss (25,649)       (25,649)  
Total comprehensive income (loss) 122         122
Balance at Dec. 31, 2021 11,952 $ 79 $ 0 432,831 (420,976) 18
Balance (in shares) at Dec. 31, 2021   7,906,728 11,357      
Increase (Decrease) in Stockholders' Equity [Roll Forward]            
Compensation expense for issuance of stock options 7,941     7,941    
Private placement -issuance of common shares and prefunded warrants, net of expenses, Shares (in shares)   2,139,843        
Private placement -issuance of common shares and prefunded warrants, net of expenses 10,857 $ 21   10,836    
Net loss (36,508)       (36,508)  
Total comprehensive income (loss) (101)         (101)
Balance at Dec. 31, 2022 $ (5,859) $ 100 $ 0 $ 451,608 $ (457,484) $ (83)
Balance (in shares) at Dec. 31, 2022   10,046,571 11,357