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Condensed Consolidated Statements of Stockholders' Equity (Deficit) (Unaudited) - USD ($) $ in Thousands | Total | Preferred F-1 Stock | Series F-2 | Common Stock | Common Stock Preferred F-1 Stock | Preferred Stock | Preferred Stock Series F-2 | Additional Paid in Capital | Additional Paid in Capital Preferred F-1 Stock | Additional Paid in Capital Series F-2 | Accumulated Deficit | Accumulated Other Comprehensive Income (Loss)
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |  |  |  |  |  |  |  |
Preferred stock, par value (in dollars per share) | $ 0.01 |  |  |  |  |  |  |  |  |  |  |
Common stock, par value (in dollars per share) | $ 0.01 |  |  |  |  |  |  |  |  |  |  |
Beginning Balance (in shares) at Dec. 31, 2021 |  |  |  | 7,906,728 |  | 11,357 |  |  |  |  |  |
Beginning Balance at Dec. 31, 2021 | $ 11,952 |  |  | $ 79 |  | $ 0 |  | $ 432,831 |  |  | $ (420,976) | $ 18
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |  |  |  |  |  |  |  |
Compensation expense for issuance of stock options | 2,271 |  |  |  |  |  |  | 2,271 |  |  |  |
Net loss | (9,000) |  |  |  |  |  |  |  |  |  | (9,000) |
Total comprehensive income | 2 |  |  |  |  |  |  |  |  |  |  | 2
Ending Balance (in shares) at Mar. 31, 2022 |  |  |  | 7,906,728 |  | 11,357 |  |  |  |  |  |
Ending Balance at Mar. 31, 2022 | 5,225 |  |  | $ 79 |  | $ 0 |  | 435,102 |  |  | (429,976) | 20
Beginning Balance (in shares) at Dec. 31, 2021 |  |  |  | 7,906,728 |  | 11,357 |  |  |  |  |  |
Beginning Balance at Dec. 31, 2021 | 11,952 |  |  | $ 79 |  | $ 0 |  | 432,831 |  |  | (420,976) | 18
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |  |  |  |  |  |  |  |
Net loss | (19,159) |  |  |  |  |  |  |  |  |  |  |
Ending Balance (in shares) at Jun. 30, 2022 |  |  |  | 7,906,728 |  | 11,357 |  |  |  |  |  |
Ending Balance at Jun. 30, 2022 | $ (2,846) |  |  | $ 79 |  | $ 0 |  | 437,221 |  |  | (440,135) | (11)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |  |  |  |  |  |  |  |
Preferred stock, par value (in dollars per share) | $ 0.01 |  |  |  |  |  |  |  |  |  |  |
Common stock, par value (in dollars per share) | $ 0.01 |  |  |  |  |  |  |  |  |  |  |
Beginning Balance (in shares) at Mar. 31, 2022 |  |  |  | 7,906,728 |  | 11,357 |  |  |  |  |  |
Beginning Balance at Mar. 31, 2022 | $ 5,225 |  |  | $ 79 |  | $ 0 |  | 435,102 |  |  | (429,976) | 20
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |  |  |  |  |  |  |  |
Compensation expense for issuance of stock options | 2,119 |  |  |  |  |  |  | 2,119 |  |  |  |
Net loss | (10,159) |  |  |  |  |  |  |  |  |  | (10,159) |
Total comprehensive income | (31) |  |  |  |  |  |  |  |  |  |  | (31)
Ending Balance (in shares) at Jun. 30, 2022 |  |  |  | 7,906,728 |  | 11,357 |  |  |  |  |  |
Ending Balance at Jun. 30, 2022 | $ (2,846) |  |  | $ 79 |  | $ 0 |  | 437,221 |  |  | (440,135) | (11)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |  |  |  |  |  |  |  |
Preferred stock, par value (in dollars per share) | $ 0.01 |  |  |  |  |  |  |  |  |  |  |
Common stock, par value (in dollars per share) | 0.01 |  |  |  |  |  |  |  |  |  |  |
Preferred stock, par value (in dollars per share) | 0.01 |  |  |  |  |  |  |  |  |  |  |
Common stock, par value (in dollars per share) | $ 0.01 |  |  |  |  |  |  |  |  |  |  |
Beginning Balance (in shares) at Dec. 31, 2022 |  |  |  | 10,046,571 |  | 11,357 |  |  |  |  |  |
Beginning Balance at Dec. 31, 2022 | $ (5,859) |  |  | $ 100 |  | $ 0 |  | 451,608 |  |  | (457,484) | (83)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |  |  |  |  |  |  |  |
Compensation expense for issuance of stock options | 1,661 |  |  |  |  |  |  | 1,661 |  |  |  |
Private placement -issuance of common shares, net of expenses (in shares) |  |  |  | 19,646 |  |  |  |  |  |  |  |
Private placement -issuance of common shares, net of expenses | 56 |  |  | $ 1 |  |  |  | 55 |  |  |  |
Issuance of common stock with the employee stock purchase plan (in shares) |  |  |  | 15,417 |  |  |  |  |  |  |  |
Issuance of common stock with the employee stock purchase plan | 47 |  |  |  |  |  |  | 47 |  |  |  |
Net loss | (9,000) |  |  |  |  |  |  |  |  |  | (9,000) |
Total comprehensive income | 19 |  |  |  |  |  |  |  |  |  |  | 19
Ending Balance (in shares) at Mar. 31, 2023 |  |  |  | 10,081,634 |  | 11,357 |  |  |  |  |  |
Ending Balance at Mar. 31, 2023 | (13,076) |  |  | $ 101 |  | $ 0 |  | 453,371 |  |  | (466,484) | (64)
Beginning Balance (in shares) at Dec. 31, 2022 |  |  |  | 10,046,571 |  | 11,357 |  |  |  |  |  |
Beginning Balance at Dec. 31, 2022 | $ (5,859) |  |  | $ 100 |  | $ 0 |  | 451,608 |  |  | (457,484) | (83)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |  |  |  |  |  |  |  |
[Series E] Warrant Exercise (in shares) |  |  | 9,624 |  |  |  |  |  |  |  |  |
Issuance of common stock related to stock option exercises (in shares) | 468 |  |  |  |  |  |  |  |  |  |  |
Net loss | $ (16,202) |  |  |  |  |  |  |  |  |  |  |
Ending Balance (in shares) at Jun. 30, 2023 |  |  |  | 15,250,469 |  | 20,981 |  |  |  |  |  |
Ending Balance at Jun. 30, 2023 | $ (242) |  |  | $ 153 |  | $ 0 |  | 473,355 |  |  | (473,686) | (64)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |  |  |  |  |  |  |  |
Preferred stock, par value (in dollars per share) | $ 0.01 |  |  |  |  |  |  |  |  |  |  |
Common stock, par value (in dollars per share) | $ 0.01 |  |  |  |  |  |  |  |  |  |  |
Beginning Balance (in shares) at Mar. 31, 2023 |  |  |  | 10,081,634 |  | 11,357 |  |  |  |  |  |
Beginning Balance at Mar. 31, 2023 | $ (13,076) |  |  | $ 101 |  | $ 0 |  | 453,371 |  |  | (466,484) | (64)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |  |  |  |  |  |  |  |
Compensation expense for issuance of stock options | 1,661 |  |  |  |  |  |  | 1,661 |  |  |  |
Stock issued during period (in shares) |  |  |  |  |  |  | 9,624 |  |  |  |  |
Stock issued during the period |  |  | $ 7,099 |  |  |  |  |  |  | $ 7,099 |  |
[Series E] Warrant Exercise (in shares) |  |  |  | 538,828 | 4,629,539 |  |  |  |  |  |  |
Prefunded warrant exercise | $ 5 | $ 11,269 |  | $ 5 | $ 47 |  |  |  | $ 11,222 |  |  |
Issuance of common stock related to stock option exercises (in shares) | 468 |  |  |  |  |  |  |  |  |  |  |
Issuance of common stock related to stock option exercises | $ 2 |  |  |  |  |  |  | 2 |  |  |  |
Net loss | (7,202) |  |  |  |  |  |  |  |  |  | (7,202) |
Ending Balance (in shares) at Jun. 30, 2023 |  |  |  | 15,250,469 |  | 20,981 |  |  |  |  |  |
Ending Balance at Jun. 30, 2023 | $ (242) |  |  | $ 153 |  | $ 0 |  | $ 473,355 |  |  | $ (473,686) | $ (64)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |  |  |  |  |  |  |  |
Preferred stock, par value (in dollars per share) | $ 0.01 |  |  |  |  |  |  |  |  |  |  |
Common stock, par value (in dollars per share) | $ 0.01 |  |  |  |  |  |  |  |  |  |  |

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