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Consolidated Statements of Stockholders' Equity (Deficit) - USD ($)
$ in Thousands
Total
Common Stock
Preferred Stock
Series F Preferred Stock
Stock options
Employee Stock
Preferred Stock
Preferred Stock
Preferred Stock
Preferred Stock
Series E
Preferred Stock
Series F Preferred Stock
Common Stock
Common Stock
Common Stock
Common Stock
Series E
Common Stock
Series F Preferred Stock
Additional Paid in Capital
Additional Paid in Capital
Common Stock
Additional Paid in Capital
Preferred Stock
Additional Paid in Capital
Series F Preferred Stock
Additional Paid in Capital
Stock options
Additional Paid in Capital
Employee Stock
Accumulated Deficit
Accumulated Comprehensive Income (Loss)
Beginning balance (in shares) at Dec. 31, 2021             11,357       7,906,728                      
Beginning balance at Dec. 31, 2021 $ 11,952           $ 0       $ 79       $ 432,831           $ (420,976) $ 18
Increase (Decrease) in Stockholders' Equity [Roll Forward]                                            
Compensation expense for issuance of stock options         $ 7,941                           $ 7,941      
Private placement -issuance of common shares and prefunded warrants, net of expenses (in shares)                     2,139,843                      
Private placement - issuance of common stock and prefunded warrants, net of expenses 10,857                   $ 21       10,836              
Net loss (36,508)                                       (36,508)  
Foreign currency translation adjustments 101                                          
Foreign currency translation adjustments (101)                                         (101)
Ending balance (in shares) at Dec. 31, 2022             11,357       10,046,571                      
Ending balance at Dec. 31, 2022 (5,859)           $ 0       $ 100       451,608           (457,484) (83)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                                            
Compensation expense for issuance of stock options         $ 8,090 $ 61                         $ 8,090 $ 61    
Stock issued during period, shares, new issues (in shares)               44,483       19,646                    
Stock issued during period, value, new issues   $ 56 $ 49,487                 $ 1       $ 55 $ 49,487          
Issuance of common stock with the employee stock purchase plan (in shares)                     41,435                      
Issuance of common stock with the employee stock purchase plan $ 123                           123              
Issuance of common stock related to stock option exercises (in shares) 819                   819                      
Issuance of common stock related to stock option exercises $ 4                           4              
Conversion of Preferred Shares to common stock (in shares)                 (100) (30,921)     10,000 12,073,145                
Conversion of Preferred Shares to common stock       $ 11,270                   $ 122       $ 11,148        
Issuance of common stock with common stock warrant exercises (in shares)                     569,938                      
Issuance of common stock with common stock warrant exercises 5                   $ 5                      
Net loss (47,678)                                       (47,678)  
Unrealized gain on investments 157                                         157
Foreign currency translation adjustments 61                                         61
Ending balance (in shares) at Dec. 31, 2023             24,819       22,761,554                      
Ending balance at Dec. 31, 2023 $ 15,777           $ 0       $ 228       $ 520,576           $ (505,162) $ 135