<SEC-DOCUMENT>0001213900-19-006939.txt : 20190423
<SEC-HEADER>0001213900-19-006939.hdr.sgml : 20190423
<ACCEPTANCE-DATETIME>20190423125550
ACCESSION NUMBER:		0001213900-19-006939
CONFORMED SUBMISSION TYPE:	8-K
PUBLIC DOCUMENT COUNT:		3
CONFORMED PERIOD OF REPORT:	20190423
ITEM INFORMATION:		Other Events
ITEM INFORMATION:		Financial Statements and Exhibits
FILED AS OF DATE:		20190423
DATE AS OF CHANGE:		20190423

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			OptimizeRx Corp
		CENTRAL INDEX KEY:			0001448431
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-BUSINESS SERVICES, NEC [7389]
		IRS NUMBER:				261265381
		STATE OF INCORPORATION:			NV
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		8-K
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38543
		FILM NUMBER:		19761220

	BUSINESS ADDRESS:	
		STREET 1:		400 WATER ST., STE. 200
		CITY:			ROCHESTER
		STATE:			MI
		ZIP:			48307
		BUSINESS PHONE:		248-651-6558

	MAIL ADDRESS:	
		STREET 1:		400 WATER ST., STE. 200
		CITY:			ROCHESTER
		STATE:			MI
		ZIP:			48307
</SEC-HEADER>
<DOCUMENT>
<TYPE>8-K
<SEQUENCE>1
<FILENAME>f8k042319_optimizerx.htm
<DESCRIPTION>CURRENT REPORT
<TEXT>
<HTML>
<HEAD>
     <TITLE></TITLE>
</HEAD>
<BODY STYLE="font: 10pt Times New Roman, Times, Serif">

<P STYLE="margin: 0">&nbsp;</P>



<P STYLE="margin: 0"></P>

<!-- Field: Rule-Page --><DIV ALIGN="LEFT" STYLE="margin-top: 0; margin-bottom: 0"><DIV STYLE="font-size: 1pt; border-top: Black 2pt solid; border-bottom: Black 1pt solid; width: 100%">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->

<P STYLE="margin: 0">&nbsp;</P>

<P STYLE="margin: 0"></P>

<P STYLE="margin: 0"></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><B>SECURITIES AND EXCHANGE COMMISSION</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 12pt; text-align: center"><B>WASHINGTON, D.C. 20549<BR>
____________________</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0.25in; text-align: center"><B>FORM 8-K</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><B>CURRENT REPORT</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><B>PURSUANT TO SECTION 13 OR 15(d) OF</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><B>THE SECURITIES EXCHANGE ACT OF 1934</B><BR>
<BR>
Date of Report (Date of earliest event reported): April 23, 2019<BR>
<BR>
<U>OptimizeRx Corporation</U><BR>
(Exact name of registrant as specified in its charter)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 34%; padding: 0; text-align: center"><U>Nevada</U></TD>
    <TD STYLE="width: 33%; padding: 0; text-align: center"><U>000-53605</U></TD>
    <TD STYLE="width: 33%; padding: 0; text-align: center"><U>26-1265381</U></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0; text-align: center">(State or other jurisdiction of incorporation)</TD>
    <TD STYLE="padding: 0; text-align: center">(Commission File Number)</TD>
    <TD STYLE="padding: 0; text-align: center">(I.R.S. Employer Identification No.)</TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; text-align: center; margin-bottom: 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 67%; padding: 0; text-align: center"><U>400 Water Street, Suite 200, Rochester, MI</U></TD>
    <TD STYLE="width: 33%; padding: 0; text-align: center"><U>48307</U></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0; text-align: center">(Address of principal executive offices)</TD>
    <TD STYLE="padding: 0; text-align: center">(Zip Code)</TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; text-align: center; margin-bottom: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; text-align: center; margin-bottom: 0">Registrant&rsquo;s telephone number, including area code: <U>248.651.6568</U></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 100%; padding: 0; text-indent: 0">
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">___________________________________________________</P>
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">(Former name or former address, if changed since
        last report)</P></TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Check the appropriate box below if the Form 8-K filing is intended
to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 4%"><FONT STYLE="font-family: Times New Roman, Times, Serif">&#9744;</FONT></TD>
    <TD STYLE="width: 96%">Written communications pursuant to Rule 425 under the Securities Act (17CFR 230.425)</TD></TR>
<TR STYLE="vertical-align: top">
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD><FONT STYLE="font-family: Times New Roman, Times, Serif">&#9744;</FONT></TD>
    <TD>Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)</TD></TR>
<TR STYLE="vertical-align: top">
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD><FONT STYLE="font-family: Times New Roman, Times, Serif">&#9744;</FONT></TD>
    <TD>Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))</TD></TR>
<TR STYLE="vertical-align: top">
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD><FONT STYLE="font-family: Times New Roman, Times, Serif">&#9744;</FONT></TD>
    <TD>Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))</TD></TR>
</TABLE>


<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Indicate by check mark whether the registrant is an emerging growth
company as defined in Rule 405 of the Securities Act of 1933 (&sect;230.405 of this chapter) or Rule 12b-2 of the Securities Exchange
Act of 1934 (&sect;240.12b-2 of this chapter).</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Emerging growth company&nbsp;&nbsp;&nbsp;&#9744;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">If an emerging growth company, indicate by check mark if the registrant
has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided
pursuant to Section 13(a) of the Exchange Act.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &#9744;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><B></B></P>

<!-- Field: Rule-Page --><DIV ALIGN="LEFT" STYLE="margin-top: 0; margin-bottom: 0"><DIV STYLE="font-size: 1pt; border-top: Black 1pt solid; border-bottom: Black 2pt solid; width: 100%">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><B></B></P>

<!-- Field: Page; Sequence: 1 -->
    <DIV STYLE="margin-top: 6pt; margin-bottom: 6pt; border-bottom: Black 1.5pt solid"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
    <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 6pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><B>SECTION 8 &ndash; Other Events</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><B>&nbsp;</B></P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0%; padding: 0; text-indent: 0"></TD><TD STYLE="width: 8%; padding: 0; text-indent: 0"><B>Item 8.01</B></TD><TD STYLE="padding: 0; text-indent: 0; width: 92%"><B>Other Events</B></TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">On April 23, 2019, we issued a press release announcing three invitations
to present at institutional investor conferences in May of this year. A copy of the press release is attached as Exhibit 99.1 to
this Current Report on Form 8-K.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The information in Item 8.01 of this Current
Report on Form 8-K (including Exhibit 99.1) shall not be deemed &ldquo;filed&rdquo; for purposes of Section 18 of the Securities
Exchange Act of 1934 (the &ldquo;Exchange Act&rdquo;) or otherwise subject to the liabilities of that section, nor shall it be
deemed incorporated by reference in any filing under the Securities Act of 1933 or the Exchange Act, except as expressly set forth
by specific reference in such a filing.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><B>SECTION 9 &ndash; Financial Statements and Exhibits</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><B>&nbsp;</B></P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0%; padding: 0; text-indent: 0"></TD><TD STYLE="width: 8%; padding: 0; text-indent: 0"><B>Item 9.01</B></TD><TD STYLE="padding: 0; text-indent: 0; width: 92%"><B>Financial Statements and Exhibits</B></TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top; text-align: justify">
    <TD STYLE="width: 0%">&nbsp;</TD>
<TD STYLE="width: 8%; text-align: left">99.1</TD><TD STYLE="text-align: justify; width: 92%"><A HREF="f8k042319ex99-1_optimizerx.htm" STYLE="-sec-extract: exhibit">Press release, dated April 23, 2019</A></TD>
</TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"></P>

<!-- Field: Page; Sequence: 2 -->
    <DIV STYLE="margin-top: 6pt; margin-bottom: 6pt; border-bottom: Black 1.5pt solid"><P STYLE="margin-top: 0pt; text-align: center; margin-bottom: 0pt"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->1<!-- Field: /Sequence -->&nbsp;</P></DIV>
    <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 6pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>SIGNATURES</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif">Pursuant
to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf
by the undersigned hereunto duly authorized.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>OptimizeRx
Corporation</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 35%; padding: 0; font-size: 10pt; text-indent: 0; border-bottom: Black 1.5pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif">/s/
    Douglas Baker</FONT></TD>
    <TD STYLE="width: 65%"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0; font-size: 10pt; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Douglas Baker</FONT></TD>
    <TD><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0; font-size: 10pt; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Chief Financial
    Officer</FONT></TD>
    <TD><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0; font-size: 10pt; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD>
    <TD><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0; font-size: 10pt; text-indent: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Date: April
    23, 2019</FONT></TD>
    <TD><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></TD></TR>
</TABLE>


<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"></P>

<!-- Field: Page; Sequence: 3; Options: Last -->
    <DIV STYLE="margin-top: 6pt; margin-bottom: 6pt; border-bottom: Black 1.5pt solid"><P STYLE="margin-top: 0pt; text-align: center; margin-bottom: 0pt"><!-- Field: Sequence; Type: Arabic; Name: PageNo -->2<!-- Field: /Sequence -->&nbsp;</P></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

</BODY>
</HTML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.1
<SEQUENCE>2
<FILENAME>f8k042319ex99-1_optimizerx.htm
<DESCRIPTION>PRESS RELEASE, DATED APRIL 23, 2019
<TEXT>
<HTML>
<HEAD>
     <TITLE></TITLE>
</HEAD>
<BODY STYLE="font: 10pt Times New Roman, Times, Serif">

<P STYLE="margin: 0"></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: right"><B>Exhibit 99.1</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: right"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><B><IMG SRC="image_001.jpg" ALT="">&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B><BR>
OptimizeRx to Present at Investor Conferences in May</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><FONT STYLE="background-color: white"><B>ROCHESTER, Mich., </B></FONT><B>(April
23, 2019) &mdash;</B> OptimizeRx Corp. (NASDAQ: OPRX), a leading digital health messaging platform for the pharmaceutical industry,
has been invited to present at three institutional investor conferences in May.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Event: Oppenheimer Emerging Growth Conference</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Date: May 14, 2019</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Location: InterContinental Barclay Hotel in NYC</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Format: 1x1 meetings</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Registration: Please contact your Oppenheimer &amp; Co. Inc. institutional
sales representative</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Event: B. Riley FBR Investor Conference</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Date: May 22-23, 2019</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Location: The Beverly Hilton Hotel in Beverly Hills, California</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Format: 1x1 meetings and presentation</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Presentation time: 1:00 p.m. Pacific time</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Webcast: click here</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Registration: email 1on1@brileyfbr.com or click here</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Event: Ladenburg Thalmann Technology Expo 2019</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Date: May 30, 2019</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Location: 101 Park Avenue in NYC</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Format: 1x1 meetings and presentation</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Presentation time: 4:00 p.m. Eastern time</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Registration: click here</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">These events are designed to give institutional analysts and investors
the opportunity to meet with OptimizeRx management. They will be discussing a number of topics, including the company&rsquo;s record
results for the fourth quarter of 2018, the acquisition of CareSpeak Communications, and growth of the company&rsquo;s digital
health platform. The network has become the largest of its kind, now reaching more than half of the ambulatory patient market in
the U.S.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">The company recently reported its seventh sequential quarter of
revenue growth, driving 2018 revenue up 75% to a record $21.2 million and the company&rsquo;s first year of profitability. The
company plans to maintain a gross margin target of at least 55% in 2019, as new digital health messaging pharma clients and programs
ramp up.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">To schedule a one-on-one meeting with OptimizeRx, you may submit
your request via the links provided upon your registration for the conferences. For any questions about the company, please contact
Ron Both of CMA at (949) 432-7557 or submit your request here.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"></P>

<!-- Field: Page; Sequence: 1; Options: NewSection; Value: 1 -->
    <DIV STYLE="margin-top: 6pt; margin-bottom: 6pt; border-bottom: Black 1.5pt solid"><P STYLE="margin: 0pt; text-align: right">&nbsp;Page <!-- Field: Sequence; Type: Arabic; Name: PageNo -->1<!-- Field: /Sequence --> of 2</P></DIV>
    <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 6pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><B>About OptimizeRx</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><FONT STYLE="background-color: white">OptimizeRx&reg; (NASDAQ: OPRX),
a digital health company,&nbsp;connects&nbsp;pharmaceutical companies to patients and providers, offering greater affordability,
adherence and brand awareness at the point-of-care. As the nation&rsquo;s largest point-of-prescribe promotional platform for the
pharmaceutical industry,&nbsp;OptimizeRx&nbsp;provides a direct channel for pharma companies to communicate with healthcare providers
right within their workflow and also directly to patients. </FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><FONT STYLE="background-color: white">The cloud-based solution supports
patient adherence to medications and better healthcare outcomes with real-time access to financial assistance, prior authorization,
education and critical clinical information.&nbsp;OptimizeRx&nbsp;provides more than half of the ambulatory patient market with
access to these benefits through leading EHR platforms like Allscripts, Amazing Charts and Quest, and directly via its mobile communications
platform.&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">For more information, follow the company on&nbsp;Twitter,&nbsp;LinkedIn&nbsp;or
visit&nbsp;www.optimizerx.com.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><B>Important Cautions Regarding Forward Looking Statements</B><BR>
This press release contains forward-looking statements within the definition of Section 27A of the Securities Act of 1933, as amended,
and such as in section 21E of the Securities Act of 1934, as amended. These forward-looking statements should not be used to make
an investment decision. The words 'estimate,' 'possible' and 'seeking' and similar expressions identify forward-looking statements,
which speak only as to the date the statement was made. The company undertakes no obligation to publicly update or revise any forward-looking
statements, whether because of new information, future events, or otherwise. Forward-looking statements are inherently subject
to risks and uncertainties, some of which cannot be predicted, or quantified. Future events and actual results could differ materially
from those set forth in, contemplated by, or underlying the forward-looking statements. The risks and uncertainties to which forward-looking
statements are subject include, but are not limited to, the effect of government regulation, competition and other material risks.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><B>OptimizeRx Contact</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Doug Baker, CFO</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Tel (248) 651-6568 x807</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">dbaker@optimizerx.com</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><B>Media Relations Contact</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Nicole Brooks, Innsena Communications</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Tel (860) 800-2344</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">nicolebrooks@innsena.com</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><B>Investor Relations Contact</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Ron Both, CMA</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Tel (949) 432-7557</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">oprx@cma.team</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"></P>

<!-- Field: Page; Sequence: 2; Options: Last -->
    <DIV STYLE="margin-top: 6pt; margin-bottom: 6pt; border-bottom: Black 1.5pt solid"><P STYLE="margin: 0pt; text-align: right">&nbsp;Page <!-- Field: Sequence; Type: Arabic; Name: PageNo -->2<!-- Field: /Sequence --> of 2</P></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

</BODY>
</HTML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>image_001.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
begin 644 image_001.jpg
M_]C_X  02D9)1@ ! 0$ 8 !@  #_VP!#  @&!@<&!0@'!P<)"0@*#!0-# L+
M#!D2$P\4'1H?'AT:'!P@)"XG("(L(QP<*#<I+# Q-#0T'R<Y/3@R/"XS-#+_
MVP!# 0D)"0P+#!@-#1@R(1PA,C(R,C(R,C(R,C(R,C(R,C(R,C(R,C(R,C(R
M,C(R,C(R,C(R,C(R,C(R,C(R,C(R,C+_P  1"  T -T# 2(  A$! Q$!_\0
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M*?'GAZSN;K7KO3-/AC$6^VP)[R0?>=GQPN> !Z&NTNO^2<S?]@D_^BJJ?#
M?#70@!_R[Y_\>-+9 <I?:GXK\'>($\-6VH/JYU6,?V;<7N"]N^[#%R/O #G\
MO>M>[\#^)(+%[NS\;ZO)JJ+O59"OD.PYV[,< ]*/%'_)7/!G_7.Y_P#0:]![
M4V[6 YWP/XBD\4>$[34YXUCN6W1SJO02*<''Y9_&LSP3JE_?^)/&$%W=2316
MFHB.W1^D:X/ ]JJ_![_D29/^O^X_]"I/A]_R-GCK_L*#^1H:W M77@OQ!/=S
MS1^.]5ACDD9UB6%"$!.0H]ATKGO""Z_J?C><6_BG4-0T+3'V3SS*@6XEQ]Q<
M#E1W/M[UN^-]:O;Z^A\&:!)MU.^7==7"_P#+I;_Q,?0D<#_ZXKJ=#T6R\/:-
M;:781[+>!=H]6/=CZDGFB]EJ!S?BG7M6N-?MO"GAIHXM0FB,]U>2+N6UASC(
M'=CV_P XK3^!/$-O#Y^G>.=7:_7YA]J*O"Y]"F.!^=8>IZ,]]\9M0M9-9U#2
MFO;&.6VDM) AF"@!DR>N,$XKH?\ A7=Y_P!#OXD_\"1_A1H@-+P1XEN/$6E3
MKJ$"V^JV$[6M[$O0.O<>Q_QK$^(O_'_8_P#7)OYBMKP=X8LO#[:E/::M<:E)
M>3 W$LTBN1(F002._/.:Q?B+_P ?]C_UR;^8KCQUO9.WD9U/A)]-\=65CIEK
M:O:7#-#$J$C;@D#ZUB^)O$8\02VT<-L\<<1.T-RSL<>E=1IOA/2+WP_;2M;!
M;B:W!,H9LAB.N,XKD]!N/["\3HEXB_*Y@D+#[ASC</3M^%<55UN6,)OW69OF
MLD]BUXL\0ZYX#\&:5'86.9'/[ZZD7<D)SNV$>ISC/3KWKHO#/C_2?$/A^34C
M(+>:W %U;L<M&W;'J#V-7O&.LZ-HOANYEUQ4FM95,8MB,F<G^$#^O;K7AO@:
MWDFM?$-W;VDB6@\H#JPC&\G;N[D#%>I)*G0;2V1N](GL.@^*[W6->E@%IFS8
M94KUA [L>^:["N3\#ZAITFF_8X(Q#=I\TJDY,G^T#W^G:NLK+#-NFFW>Y,-@
MKF/%'@72_$\L5W(TUGJ4/^IOK5MDB^F?45T]%;IV*//QX5\?0+Y$'CI'AZ!Y
MK%6DQ]:M:-\.+6UU5-8US4;K7-33F.6[^Y&?]E.@KMJ*KF87&3?ZB3_=/\J\
M>\ >#8]9\'6>K6&HW.DZO%-/&+NVP?,3S#\KJ>&%>Q2*7C91U((KG? OARY\
M*^&(]+NIXII4ED<O$"%PS$CK0G9 8L_@/7-:46_B/Q?<W=AGY[6U@6W$H]&(
MY(KM[.SMM/LH;.SA2&WA0)'&@P% [5/12;; XW6?!5]/XED\0:!KCZ5?3Q+%
M<@P+*DH'0X/0BK^I>&)]8\#S>';_ %66:>:())?&(!F.X-G;T[8KHZ*+L#/E
MTM9/#SZ3YI"M:FV\S'.-FW.*B\-:(OASPY8Z0D[3K:Q[!*R[2W).<?C6K12N
M!@:GX834O%>CZZ;IXVTU9%$(0$2;QCD]L5OT447 P?"/AE/"FBMIT=TUR&GD
MFWL@4_,<XP/2C0/#*:%JNMWRW33'5;G[0R,@ C// /?K6]13NP/.K?X9ZI9Z
ME>W]IXSOH+F]DWSR+;(6?DX&2>@STK3L?"'B&UU"WN)_'.HW,,4BN\#V\860
M \J2.QKLJ*?,QW,#Q1X2T_Q3;PBY>6WN[9M]M>6[;986]0?3VK!D\&^+KF(V
MESX\N/LA&"8K-$F8>F\'CZUWM%)-H1D^'?#NG>%])33M-C98@Q=W<Y>1SU9C
MW)JKXB\,+K\\$K7;0>4I7 3=G)^M=!143@JBM(35]RM86HL=/M[0.7$,83<1
MC.!UK!UWP;!K.H&\%TUN[*%<!-P8COU]*Z>BIG2A./+): TFK,XWQ/\ #VT\
M5:18VU[>2K>68"I>(O)7C<"N<<@?GS[5T6DZ+I^B:3%IEA;K':QKMV8SN]2W
MJ3W-:%%:+:W09S^G^$;#3M8DU"(L>\41Z1$]<>OMZ5T%%%3"$8*T58226P44
M450PHHHH **** "BBB@ HHHH **** "BBB@ HHHH **** "BBB@ HHHH ***
,* "BBB@ HHHH __9

end
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
