EX-23.1 8 pacb-20161231xex23_1.htm EX-23.1

Exhibit 23.1

CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

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We consent to the incorporation by reference in the following Registration Statements:

| (1) |  | Registration Statements (Forms S-8, Nos. 333-170211, 333-179810, 333-186065, 333-193437, 333-201678, 333-209157 and 333-215746) pertaining to the 2010 Equity Incentive Plan, 2010 Employee Stock Purchase Plan, and 2010 Outside Director Equity Incentive Plan of Pacific Biosciences of California, Inc., and

| (2) |  | Registration Statements (Forms S-3, Nos. 333-180533, 333-187363 and 333-199891) and related Prospectuses of Pacific Biosciences of California, Inc.;

of our reports dated March 6, 2017, with respect to the consolidated financial statements of Pacific Biosciences of California, Inc. and the effectiveness of internal control over financial reporting of Pacific B iosciences of California, Inc. included in this Annual Report (Form 10-K) of Pacific Biosciences of California, Inc. for the year ended December 31, 2016.

/s/ Ernst & Young LLP

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Redwood City, California

March 6, 2017

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