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Consolidated Statements Of Operations And Comprehensive Loss - USD ($)
shares in Thousands, $ in Thousands
 12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Revenue:      
Product revenue $ 64,609 $ 37,502 $ 35,299
Service and other revenue 13,971 10,896 8,511
Contractual revenue 12,134 44,384 16,784
Total revenue 90,714 92,782 60,594
Cost of Revenue:      
Cost of product revenue 34,512 30,704 29,626
Cost of service and other revenue 12,042 8,628 7,566
Total cost of revenue 46,554 39,332 37,192
Gross profit 44,160 53,450 23,402
Operating Expense:      
Research and development 67,617 60,440 48,230
Sales, general and administrative 47,787 45,187 38,026
Gain on lease amendments   (23,043)  
Total operating expense 115,404 82,584 86,256
Operating loss (71,244) (29,134) (62,854)
Interest expense (3,234) (2,926) (2,828)
Other income (expense), net 103 364 (478)
Net loss (74,375) (31,696) (66,160)
Other comprehensive loss:      
Unrealized gain (loss) on investments 12 (16) (5)
Comprehensive loss $ (74,363) $ (31,712) $ (66,165)
Net loss per share:      
Basic and diluted net loss per share $ (0.83) $ (0.42) $ (0.94)
Shares used in computing basic and diluted net loss per share 89,148 75,614 70,475