<SEC-DOCUMENT>0001193125-17-245843-index.html : 20170802
<SEC-HEADER>0001193125-17-245843.hdr.sgml : 20170802
<ACCEPTANCE-DATETIME>20170802163742
ACCESSION NUMBER:		0001193125-17-245843
CONFORMED SUBMISSION TYPE:	S-3
PUBLIC DOCUMENT COUNT:		7
FILED AS OF DATE:		20170802
DATE AS OF CHANGE:		20170802

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			PACIFIC BIOSCIENCES OF CALIFORNIA, INC.
		CENTRAL INDEX KEY:			0001299130
		STANDARD INDUSTRIAL CLASSIFICATION:	LABORATORY ANALYTICAL INSTRUMENTS [3826]
		IRS NUMBER:				161590339
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-3
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-219642
		FILM NUMBER:		171000441

	BUSINESS ADDRESS:	
		STREET 1:		1305 O'BRIEN DRIVE
		CITY:			MENLO PARK
		STATE:			CA
		ZIP:			94025
		BUSINESS PHONE:		650-521-8000

	MAIL ADDRESS:	
		STREET 1:		1305 O'BRIEN DRIVE
		CITY:			MENLO PARK
		STATE:			CA
		ZIP:			94025

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	PACIFIC BIOSCIENCES OF CALIFORNIA INC
		DATE OF NAME CHANGE:	20050829

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	NANOFLUIDICS INC
		DATE OF NAME CHANGE:	20040729
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-3
<SEQUENCE>1
<FILENAME>d417648ds3.htm
<DESCRIPTION>FORM S-3
<TEXT>
Document 1 - file: d417648ds3.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.2
<SEQUENCE>2
<FILENAME>d417648dex42.htm
<DESCRIPTION>EX-4.2
<TEXT>
Document 2 - file: d417648dex42.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.4
<SEQUENCE>3
<FILENAME>d417648dex44.htm
<DESCRIPTION>EX-4.4
<TEXT>
Document 3 - file: d417648dex44.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>4
<FILENAME>d417648dex51.htm
<DESCRIPTION>EX-5.1
<TEXT>
Document 4 - file: d417648dex51.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-12.1
<SEQUENCE>5
<FILENAME>d417648dex121.htm
<DESCRIPTION>EX-12.1
<TEXT>
Document 5 - file: d417648dex121.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>6
<FILENAME>d417648dex231.htm
<DESCRIPTION>EX-23.1
<TEXT>
Document 6 - file: d417648dex231.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>7
<FILENAME>g417648g53x69.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 7 - file: g417648g53x69.jpg

</DOCUMENT>
</SEC-DOCUMENT>