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v3.8.0.1

Consolidated Statements Of Cash Flows - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2017 | Dec. 31, 2016 | Dec. 31, 2015
Cash flows from operating activities |  |  |
Net loss | $ (92,189) | $ (74,375) | $ (31,696)
Adjustments to reconcile net loss to net cash used in operating activities |  |  |
Depreciation and amortization | 8,442 | 3,875 | 3,677
Amortization of debt discount and financing costs | 1,203 | 1,158 | 957
Stock-based compensation | 20,352 | 19,562 | 13,840
Non-cash portion of gain on lease amendments |  |  | (3,043)
(Gain) Loss from derivative | 653 | (244) | (344)
Other items | 47 | 97 | 114
Changes in assets and liabilities |  |  |
Accounts receivable | (2,012) | (6,176) | (1,738)
Inventory | (8,442) | (6,151) | (2,466)
Prepaid expenses and other assets | 7,803 | (202) | (17,889)
Accounts payable | 764 | 3,402 | (716)
Accrued expenses | (3,986) | 1,053 | 5,732
Deferred service revenue | (1,033) | 469 | 708
Deferred contractual revenue |  | (12,134) | (14,386)
Other liabilities | 880 | 1,737 | (639)
Net cash used in operating activities | (67,518) | (67,929) | (47,889)
Cash flows from investing activities |  |  |
Purchase of property and equipment | (10,433) | (8,207) | (3,009)
Proceeds from disposal of property and equipment | 41 | 10 | 36
Long-term restricted cash |  |  | (4,500)
Purchase of investments | (86,339) | (95,848) | (84,579)
Sales of investments | 7,111 | 23,285 | 8,317
Maturities of investments | 88,071 | 65,896 | 92,341
Net cash provided by (used in) investing activities | (1,549) | (14,864) | 8,606
Cash flows from financing activities |  |  |
Proceeds from issuance of common stock from equity plans | 8,914 | 7,729 | 7,363
Notes payable principal payoff | (4,500) |  |
Net cash provided by financing activities | 68,809 | 65,929 | 36,463
Net decrease in cash and cash equivalents | (258) | (16,864) | (2,820)
Cash and cash equivalents at beginning of period | 16,765 | 33,629 | 36,449
Cash and cash equivalents at end of period | 16,507 | 16,765 | 33,629
Supplemental disclosure of cash flow information |  |  |
Interest paid | 1,687 | 1,799 | 1,794
Supplemental disclosure of non-cash investing and financing activities |  |  |
Inventory transferred to property and equipment | 1,267 | 1,282 | 2,846
Property and equipment paid by landlord | 12,600 |  |
Changes in deposits for property and equipment paid in prior period | 9,694 |  |
Property and equipment returned to landlord | 1,854 |  |
At the Market Offering [Member] |  |  |
Cash flows from financing activities |  |  |
Proceeds from issuance of common stock from offering, net of issuance costs | 11,865 | $ 58,200 | $ 29,100
Underwritten Public Equity Offering [Member] |  |  |
Cash flows from financing activities |  |  |
Proceeds from issuance of common stock from offering, net of issuance costs | $ 52,530 |  |

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- Definition The cash outflow for a borrowing supported by a written promise to pay an obligation. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 15 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3291-108585 + Details
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- Definition The aggregate amount of noncash, equity-based employee remuneration. This may include the value of stock or unit options, amortization of restricted stock or units, and adjustment for officers' compensation. As noncash, this element is an add back when calculating net cash generated by operating activities using the indirect method. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3602-108585 + Details
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- References No definition available. + Details
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