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Consolidated Statements Of Operations And Comprehensive Loss - USD ($)
shares in Thousands, $ in Thousands
 12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Revenue:      
Product revenue $ 80,030 $ 64,609 $ 37,502
Service and other revenue 13,438 13,971 10,896
Contractual revenue   12,134 44,384
Total revenue 93,468 90,714 92,782
Cost of Revenue:      
Cost of product revenue 42,900 34,512 30,704
Cost of service and other revenue 15,909 12,042 8,628
Total cost of revenue 58,809 46,554 39,332
Gross profit 34,659 44,160 53,450
Operating expense:      
Research and development 65,324 67,617 60,440
Sales, general and administrative 59,119 47,787 45,187
Gain on lease amendments     (23,043)
Total operating expense 124,443 115,404 82,584
Operating loss (89,784) (71,244) (29,134)
Interest expense (2,921) (3,234) (2,926)
Other income (expense), net 516 103 364
Net loss (92,189) (74,375) (31,696)
Other comprehensive loss:      
Unrealized gain (loss) on investments (37) 12 (16)
Comprehensive loss $ (92,226) $ (74,363) $ (31,712)
Net loss per share:      
Basic and diluted net loss per share $ (0.87) $ (0.83) $ (0.42)
Shares used in computing basic and diluted net loss per share 105,682 89,148 75,614