<SEC-DOCUMENT>0001144204-18-008990-index.html : 20180214
<SEC-HEADER>0001144204-18-008990.hdr.sgml : 20180214
<ACCEPTANCE-DATETIME>20180214165044
ACCESSION NUMBER:		0001144204-18-008990
CONFORMED SUBMISSION TYPE:	SC 13G/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20180214
DATE AS OF CHANGE:		20180214
GROUP MEMBERS:		FEINBERG FAMILY FOUNDATION
GROUP MEMBERS:		ORACLE ASSOCIATES, LLC
GROUP MEMBERS:		ORACLE INSTITUTIONAL PARTNERS, L.P.
GROUP MEMBERS:		ORACLE INVESTMENT MANAGEMENT EMPLOYEES RETIREMENT FUND
GROUP MEMBERS:		ORACLE INVESTMENT MANAGEMENT, INC.
GROUP MEMBERS:		ORACLE PARTNERS, L.P.
GROUP MEMBERS:		ORACLE TEN FUND MASTER, LP

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			PACIFIC BIOSCIENCES OF CALIFORNIA, INC.
		CENTRAL INDEX KEY:			0001299130
		STANDARD INDUSTRIAL CLASSIFICATION:	LABORATORY ANALYTICAL INSTRUMENTS [3826]
		IRS NUMBER:				161590339
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-85738
		FILM NUMBER:		18613011

	BUSINESS ADDRESS:	
		STREET 1:		1305 O'BRIEN DRIVE
		CITY:			MENLO PARK
		STATE:			CA
		ZIP:			94025
		BUSINESS PHONE:		650-521-8000

	MAIL ADDRESS:	
		STREET 1:		1305 O'BRIEN DRIVE
		CITY:			MENLO PARK
		STATE:			CA
		ZIP:			94025

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	PACIFIC BIOSCIENCES OF CALIFORNIA INC
		DATE OF NAME CHANGE:	20050829

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	NANOFLUIDICS INC
		DATE OF NAME CHANGE:	20040729

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			FEINBERG LARRY N
		CENTRAL INDEX KEY:			0000926475
		STATE OF INCORPORATION:			NY

	FILING VALUES:
		FORM TYPE:		SC 13G/A

	MAIL ADDRESS:	
		STREET 1:		C/O ORACLE PARTNERS L P
		STREET 2:		200 GREENWICH AVENUE
		CITY:			GREENWICH
		STATE:			CT
		ZIP:			06830
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13G/A
<SEQUENCE>1
<FILENAME>tv486163_sc13ga.htm
<DESCRIPTION>AMENDMENT NO. 2
<TEXT>
Document 1 - file: tv486163_sc13ga.htm

</DOCUMENT>
</SEC-DOCUMENT>