<SEC-DOCUMENT>0001193125-18-342511-index.html : 20181206
<SEC-HEADER>0001193125-18-342511.hdr.sgml : 20181206
<ACCEPTANCE-DATETIME>20181204215918
ACCESSION NUMBER:		0001193125-18-342511
CONFORMED SUBMISSION TYPE:	PREM14A
PUBLIC DOCUMENT COUNT:		5
CONFORMED PERIOD OF REPORT:	20181204
FILED AS OF DATE:		20181205
DATE AS OF CHANGE:		20181204

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			PACIFIC BIOSCIENCES OF CALIFORNIA, INC.
		CENTRAL INDEX KEY:			0001299130
		STANDARD INDUSTRIAL CLASSIFICATION:	LABORATORY ANALYTICAL INSTRUMENTS [3826]
		IRS NUMBER:				161590339
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		PREM14A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-34899
		FILM NUMBER:		181218575

	BUSINESS ADDRESS:	
		STREET 1:		1305 O'BRIEN DRIVE
		CITY:			MENLO PARK
		STATE:			CA
		ZIP:			94025
		BUSINESS PHONE:		650-521-8000

	MAIL ADDRESS:	
		STREET 1:		1305 O'BRIEN DRIVE
		CITY:			MENLO PARK
		STATE:			CA
		ZIP:			94025

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	PACIFIC BIOSCIENCES OF CALIFORNIA INC
		DATE OF NAME CHANGE:	20050829

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	NANOFLUIDICS INC
		DATE OF NAME CHANGE:	20040729
</SEC-HEADER>
<DOCUMENT>
<TYPE>PREM14A
<SEQUENCE>1
<FILENAME>d646626dprem14a.htm
<DESCRIPTION>PRELIMINARY PROXY STATEMENT PERTAINING TO A MERGER
<TEXT>
Document 1 - file: d646626dprem14a.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>2
<FILENAME>g646626g30p56.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 2 - file: g646626g30p56.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>g646626g53x69.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 3 - file: g646626g53x69.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>g646626img002v.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 4 - file: g646626img002v.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>g646626v001.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 5 - file: g646626v001.jpg

</DOCUMENT>
</SEC-DOCUMENT>