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Balance Sheet Components (Components of Property and Equipment, Net) (Details) - USD ($) $ in Thousands	Dec. 31, 2018	Dec. 31, 2017
Property, Plant and Equipment [Line Items]
Property and equipment	$ 71,180	$ 70,114
Less: Accumulated depreciation	(37,107)	(32,194)
Property and equipment, net	34,073	37,920
Laboratory Equipment And Machinery [Member]
Property, Plant and Equipment [Line Items]
Property and equipment	24,111	24,703
Leasehold Improvements [Member]
Property, Plant and Equipment [Line Items]
Property and equipment	29,821	29,728
Computer Equipment [Member]
Property, Plant and Equipment [Line Items]
Property and equipment	9,484	8,301
Software [Member]
Property, Plant and Equipment [Line Items]
Property and equipment	4,734	4,615
Furniture and Fixtures [Member]
Property, Plant and Equipment [Line Items]
Property and equipment	2,422	2,382
Construction in Progress [Member]
Property, Plant and Equipment [Line Items]
Property and equipment	$ 608	$ 385

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- Definition

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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Amount before accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

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