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Stockholders' Equity (Narrative) (Details)
$ / shares in Units, $ in Thousands
1 Months Ended 3 Months Ended 12 Months Ended
Aug. 18, 2017
USD ($)
Sep. 30, 2018
USD ($)
$ / shares
shares
Feb. 28, 2018
USD ($)
$ / shares
shares
Mar. 31, 2019
USD ($)
item
$ / shares
shares
Mar. 31, 2018
USD ($)
shares
Dec. 31, 2018
USD ($)
$ / shares
item
shares
Jan. 31, 2019
shares
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]              
Amount of common stock, preferred stock, depositiry shares, warrants, units or debt securities available in future public offerings | $ $ 150,000            
Common stock, preferred stock, depositiry shares, warrants, units or debt securities available in future public offerings, period from effective date 3 years            
Common Stock, par value | $ / shares       $ 0.001   $ 0.001  
Proceeds from issuance of common stock from underwritten public equity offering, net of issuance costs | $         $ 32,986    
Number of equity compensation plans | item       3      
Share-based compensation expense | $       $ 4,381 $ 5,282    
2010 Plan [Member]              
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]              
Common stock reserved for issuance | shares             7,500,000
ESPP [Member]              
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]              
Shares issued | shares       1,306,329 1,113,790    
Common stock reserved for issuance | shares       3,651,066     3,000,000
Underwritten Public Equity Offering [Member]              
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]              
Shares authorized, underwriting agreement | shares   14,117,647 12,500,000        
Common Stock, par value | $ / shares   $ 0.001 $ 0.001        
Common stock offering price per share | $ / shares   $ 4.25 $ 2.40        
Option to purchase additional shares, period   30 days 30 days        
Additional shares authorized, underwriting agreement | shares   2,117,647 1,875,000        
Shares issued | shares   16,200,000 14,400,000     30,600,000  
Price per share | $ / shares   $ 4.25 $ 2.40     $ 3.38  
Commissions, percentage of gross proceeds   6.00% 4.00%        
Proceeds from issuance of common stock from underwritten public equity offering, net of issuance costs | $   $ 64,900 $ 33,100     $ 97,500  
Other accrued offering expenses | $   $ 200 $ 300        
Holders may elect to receive net proceeds from financing activities, percentage           25.00%  
Number of offerings | item           2  
Time-Based Restricted Stock Units (RSUs) [Member] | 2010 Plan [Member]              
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]              
Vesting period       4 years      
Share-based compensation expense | $       $ 658 $ 19    
Time-Based Restricted Stock Units (RSUs) [Member] | 2010 Plan [Member] | Share-based Compensation Award, Tranche One, Two, Three and Four [Member]              
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]              
Vesting percentage       25.00%      
Performance-Based Restricted Stock Units (RSUs) [Member]              
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]              
Ratio of number of shares into which the share instrument may be converted | shares       1      
Performance-Based Restricted Stock Units (RSUs) [Member] | 2010 Plan [Member]              
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]              
Share-based compensation expense | $       $ 7 $ 90